Age-dependent pattern of cerebellar susceptibility to bilirubin neurotoxicity in vivo in mice.
about
Impairment of enzymatic antioxidant defenses is associated with bilirubin-induced neuronal cell death in the cerebellum of Ugt1 KO mice.A translationally optimized AAV-UGT1A1 vector drives safe and long-lasting correction of Crigler-Najjar syndrome.Inflammatory signature of cerebellar neurodegeneration during neonatal hyperbilirubinemia in Ugt1 -/- mouse model.Evaluation of region selective bilirubin-induced brain damage as a basis for a pharmacological treatment.Promoterless gene targeting without nucleases rescues lethality of a Crigler-Najjar syndrome mouse model.Albumin administration prevents neurological damage and death in a mouse model of severe neonatal hyperbilirubinemia.Modulation of bilirubin neurotoxicity by the Abcb1 transporter in the Ugt1-/- lethal mouse model of neonatal hyperbilirubinemia.Neuroinflammation and ER-stress are key mechanisms of acute bilirubin toxicity and hearing loss in a mouse model
P2860
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P2860
Age-dependent pattern of cerebellar susceptibility to bilirubin neurotoxicity in vivo in mice.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Age-dependent pattern of cereb ...... neurotoxicity in vivo in mice.
@en
Age-dependent pattern of cereb ...... neurotoxicity in vivo in mice.
@nl
type
label
Age-dependent pattern of cereb ...... neurotoxicity in vivo in mice.
@en
Age-dependent pattern of cereb ...... neurotoxicity in vivo in mice.
@nl
prefLabel
Age-dependent pattern of cereb ...... neurotoxicity in vivo in mice.
@en
Age-dependent pattern of cereb ...... neurotoxicity in vivo in mice.
@nl
P2093
P2860
P356
P1476
Age-dependent pattern of cereb ...... neurotoxicity in vivo in mice.
@en
P2093
Giulia Bortolussi
Giulia Viviani
Simone Vodret
Tamara Bittolo
P2860
P304
P356
10.1242/DMM.016535
P577
2014-07-25T00:00:00Z