Effect of polyamine depletion on macromolecular synthesis of the malarial parasite, Plasmodium falciparum, cultured in human erythrocytes
about
Plasmodium falciparum spermidine synthase inhibition results in unique perturbation-specific effects observed on transcript, protein and metabolite levels.Bis(benzyl)polyamine analogs inhibit the growth of chloroquine-resistant human malaria parasites (Plasmodium falciparum) in vitro and in combination with alpha-difluoromethylornithine cure murine malaria.Discovery of novel alkylated (bis)urea and (bis)thiourea polyamine analogues with potent antimalarial activities.Deletion mutagenesis of large areas in Plasmodium falciparum genes: a comparative study.Interrogating alkyl and arylalkylpolyamino (bis)urea and (bis)thiourea isosteres as potent antimalarial chemotypes against multiple lifecycle forms of Plasmodium falciparum parasites.Novel Plasmodium falciparum metabolic network reconstruction identifies shifts associated with clinical antimalarial resistance.3-Aminooxy-1-aminopropane and derivatives have an antiproliferative effect on cultured Plasmodium falciparum by decreasing intracellular polyamine concentrations.Effect of polyamines on the activity of malarial alpha-like DNA polymerase.Characterization of simian malarial parasite (Plasmodium knowlesi)-induced putrescine transport in rhesus monkey erythrocytes. A novel putrescine conjugate arrests in vitro growth of simian malarial parasite (Plasmodium knowlesi) and cures multidrug
P2860
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P2860
Effect of polyamine depletion on macromolecular synthesis of the malarial parasite, Plasmodium falciparum, cultured in human erythrocytes
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
1987年论文
@zh
1987年论文
@zh-cn
name
Effect of polyamine depletion ...... cultured in human erythrocytes
@en
Effect of polyamine depletion ...... cultured in human erythrocytes
@nl
type
label
Effect of polyamine depletion ...... cultured in human erythrocytes
@en
Effect of polyamine depletion ...... cultured in human erythrocytes
@nl
prefLabel
Effect of polyamine depletion ...... cultured in human erythrocytes
@en
Effect of polyamine depletion ...... cultured in human erythrocytes
@nl
P2093
P2860
P921
P356
P1433
P1476
Effect of polyamine depletion ...... cultured in human erythrocytes
@en
P2093
P2860
P304
P356
10.1042/BJ2420221
P407
P577
1987-02-01T00:00:00Z