Low level of Lck kinase in Th2 cells limits expression of CD4 co-receptor and S73 phosphorylation of transcription factor c-Jun

about

Low level of Lck kinase in Th2 cells limits expression of CD4 co-receptor and S73 phosphorylation of transcription factor c-Jun

Item

http://www.wikidata.org/entity/Q42246262

description

2017 nî lūn-bûn

@nan

2017年の論文

@ja

2017年論文

@yue

2017年論文

@zh-hant

2017年論文

@zh-hk

2017年論文

@zh-mo

2017年論文

@zh-tw

2017年论文

@wuu

2017年论文

@zh

2017年论文

@zh-cn

name

Low level of Lck kinase in Th2 ...... of transcription factor c-Jun

@en

Low level of Lck kinase in Th2 ...... of transcription factor c-Jun

@nl

type

Item

label

Low level of Lck kinase in Th2 ...... of transcription factor c-Jun

@en

Low level of Lck kinase in Th2 ...... of transcription factor c-Jun

@nl

prefLabel

Low level of Lck kinase in Th2 ...... of transcription factor c-Jun

@en

Low level of Lck kinase in Th2 ...... of transcription factor c-Jun

@nl

P1476

Low level of Lck kinase in Th2 ...... of transcription factor c-Jun

@en

P2093

Sergei A Nedospasov

http://www.w3.org/2001/XMLSchema#string

Silke Stanislawiak

http://www.w3.org/2001/XMLSchema#string

Taisiya R Bezhaeva

http://www.w3.org/2001/XMLSchema#string

Yury V Shebzukhov

http://www.w3.org/2001/XMLSchema#string

P2860

p56Lck anchors CD4 to distinct microdomains on microvilli.

JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation

Fyn and ZAP-70 are required for Vav phosphorylation in T cells stimulated by antigen-presenting cells

Th2-specific immunity and function of peripheral T cells is regulated by the p56Lck Src homology 3 domain.

Proline residues in CD28 and the Src homology (SH)3 domain of Lck are required for T cell costimulation

Regulation of naive T cell differentiation by varying the potency of TCR signal transduction.

Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs.

Early events of TCR signaling are distinct in human Th1 and Th2 cells.

Decreased CD4 expression by polarized T helper 2 cells contributes to suboptimal TCR-induced phosphorylation and reduced Ca2+ signaling

Functional involvement of dual specificity phosphatase 16 (DUSP16), a c-Jun N-terminal kinase-specific phosphatase, in the regulation of T helper cell differentiation

P2888

s41598-017-02553-y

P304

2339

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/S41598-017-02553-Y

http://www.w3.org/2001/XMLSchema#string

P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Dmitry Kuprash

P577

2017-05-24T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

28539628

http://www.w3.org/2001/XMLSchema#string

P932

5443812

http://www.w3.org/2001/XMLSchema#string