Parathyroid hormone-related peptide represses chondrocyte hypertrophy through a protein phosphatase 2A/histone deacetylase 4/MEF2 pathway. - Wikidata - wikimedia - TriplyDB

Parathyroid hormone-related peptide represses chondrocyte hypertrophy through a protein phosphatase 2A/histone deacetylase 4/MEF2 pathway.

Parathyroid hormone-related peptide represses chondrocyte hypertrophy through a protein phosphatase 2A/histone deacetylase 4/MEF2 pathway.

http://www.wikidata.org/entity/Q42250004

about

MicroRNA networks regulate development of brown adipocytes A pathway to bone: signaling molecules and transcription factors involved in chondrocyte development and maturation Role of G-proteins in the differentiation of epiphyseal chondrocytes Relating the chondrocyte gene network to growth plate morphology: from genes to phenotype Regulation of class IIa HDAC activities: it is not only matter of subcellular localization Post-translational modifications regulate class IIa histone deacetylase (HDAC) function in health and disease Histone deacetylase 7 (Hdac7) suppresses chondrocyte proliferation and β-catenin activity during endochondral ossification HDAC4 integrates PTH and sympathetic signaling in osteoblasts.Parathyroid hormone regulates histone deacetylase (HDAC) 4 through protein kinase A-mediated phosphorylation and dephosphorylation in osteoblastic cells HDAC4: mechanism of regulation and biological functions Indian hedgehog signaling regulates transcription and expression of collagen type X via Runx2/Smads interactions.Zfp521 is a target gene and key effector of parathyroid hormone-related peptide signaling in growth plate chondrocytes.The roles of parathyroid hormone-like hormone during mouse preimplantation embryonic development.Calcium/calmodulin-dependent protein kinase II activity regulates the proliferative potential of growth plate chondrocytes.Vertebrate skeletogenesis HDAC5 controls MEF2C-driven sclerostin expression in osteocytes.Deletion of Zfp521 rescues the growth plate phenotype in a mouse model of Jansen metaphyseal chondrodysplasia Gsα enhances commitment of mesenchymal progenitors to the osteoblast lineage but restrains osteoblast differentiation in mice.Strategies to minimize hypertrophy in cartilage engineering and regeneration.Histone Deacetylase 3 and 4 Complex Stimulates the Transcriptional Activity of the Mineralocorticoid Receptor.Sox9 directs hypertrophic maturation and blocks osteoblast differentiation of growth plate chondrocytes Crucial Role of Elovl6 in Chondrocyte Growth and Differentiation during Growth Plate Development in Mice.Histone Deacetylases in Bone Development and Skeletal Disorders.Parathyroid hormone-related protein: an update.Regulation of SIK1 abundance and stability is critical for myogenesis Development of the endochondral skeleton Inhibitory function of parathyroid hormone-related protein on chondrocyte hypertrophy: the implication for articular cartilage repair Parathyroid hormone receptor signalling in osterix-expressing mesenchymal progenitors is essential for tooth root formation.SIKs control osteocyte responses to parathyroid hormone Acrodysostosis syndromes.Class IIa HDACs: from important roles in differentiation to possible implications in tumourigenesis.CaMKII Signaling Stimulates Mef2c Activity In Vitro but Only Minimally Affects Murine Long Bone Development in vivo.MicroRNA-140 Provides Robustness to the Regulation of Hypertrophic Chondrocyte Differentiation by the PTHrP-HDAC4 Pathway.Insights from human genetic studies into the pathways involved in osteoarthritis.Overview of skeletal development.Current understanding on the molecular basis of chondrogenesis.The chondrocytic journey in endochondral bone growth and skeletal dysplasia.Chondrocyte hypertrophy in skeletal development, growth, and disease.Sphingolipid metabolism and its role in the skeletal tissues.Parathyroid Hormone-Related Protein, Its Regulation of Cartilage and Bone Development, and Role in Treating Bone Diseases.

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P2860

Parathyroid hormone-related peptide represses chondrocyte hypertrophy through a protein phosphatase 2A/histone deacetylase 4/MEF2 pathway.

http://www.wikidata.org/entity/Q42250004

description

2009 nî lūn-bûn

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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2009年论文

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2009年论文

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name

Parathyroid hormone-related pe ...... ne deacetylase 4/MEF2 pathway.

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Parathyroid hormone-related pe ...... ne deacetylase 4/MEF2 pathway.

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type

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Parathyroid hormone-related pe ...... ne deacetylase 4/MEF2 pathway.

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Parathyroid hormone-related pe ...... ne deacetylase 4/MEF2 pathway.

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Parathyroid hormone-related pe ...... ne deacetylase 4/MEF2 pathway.

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Parathyroid hormone-related pe ...... ne deacetylase 4/MEF2 pathway.

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Molecular and Cellular Biology

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Parathyroid hormone-related pe ...... ne deacetylase 4/MEF2 pathway.

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P2093

Andrew B Lassar

http://www.w3.org/2001/XMLSchema#string

Elena Kozhemyakina

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Todd Cohen

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Tso-Pang Yao

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P2860

Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3-3-dependent cellular localization

Regulation of histone deacetylase 4 by binding of 14-3-3 proteins

Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation

Activation of the myocyte enhancer factor-2 transcription factor by calcium/calmodulin-dependent protein kinase-stimulated binding of 14-3-3 to histone deacetylase 5

CaM kinase II selectively signals to histone deacetylase 4 during cardiomyocyte hypertrophy

PP2A regulates HDAC4 nuclear import

Protein phosphatase 2A controls the activity of histone deacetylase 7 during T cell apoptosis and angiogenesis

Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling

Identification of a signal-responsive nuclear export sequence in class II histone deacetylases

Mutational analysis of the DNA binding, dimerization, and transcriptional activation domains of MEF2C

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5751-5762

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10.1128/MCB.00415-09

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21

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29

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2772746

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