FKS mutations and elevated echinocandin MIC values among Candida glabrata isolates from U.S. population-based surveillance. - Wikidata - wikimedia - TriplyDB

FKS mutations and elevated echinocandin MIC values among Candida glabrata isolates from U.S. population-based surveillance.

FKS mutations and elevated echinocandin MIC values among Candida glabrata isolates from U.S. population-based surveillance.

http://www.wikidata.org/entity/Q42250085

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Microbial Biotransformation to Obtain New Antifungals Mechanisms of Candida biofilm drug resistance Global analysis of the evolution and mechanism of echinocandin resistance in Candida glabrata Echinocandin resistance: an emerging clinical problem?Epidemiology and Risk Factors for Echinocandin Nonsusceptible Candida glabrata Bloodstream Infections: Data From a Large Multisite Population-Based Candidemia Surveillance Program, 2008-2014 Breakthrough invasive Candida glabrata in patients on micafungin: a novel FKS gene conversion correlated with sequential elevation of MIC.Role of FKS Mutations in Candida glabrata: MIC values, echinocandin resistance, and multidrug resistance.Regulatory circuitry governing fungal development, drug resistance, and disease.Species identification and antifungal susceptibility testing of Candida bloodstream isolates from population-based surveillance studies in two U.S. cities from 2008 to 2011.Elucidating drug resistance in human fungal pathogens.Comparative evaluation of a new commercial colorimetric microdilution assay (SensiQuattro Candida EU) with MIC test strip and EUCAST broth microdilution methods for susceptibility testing of invasive Candida isolates.Candida glabrata mutants demonstrating paradoxical reduced caspofungin susceptibility but increased micafungin susceptibility Frequency of decreased susceptibility and resistance to echinocandins among fluconazole-resistant bloodstream isolates of Candida glabrata.Innate inflammatory response and immunopharmacologic activity of micafungin, caspofungin, and voriconazole against wild-type and FKS mutant Candida glabrata isolates.Recurrent episodes of candidemia due to Candida glabrata with a mutation in hot spot 1 of the FKS2 gene developed after prolonged therapy with caspofungin Progress in antifungal susceptibility testing of Candida spp. by use of Clinical and Laboratory Standards Institute broth microdilution methods, 2010 to 2012 The presence of an FKS mutation rather than MIC is an independent risk factor for failure of echinocandin therapy among patients with invasive candidiasis due to Candida glabrata.Invasive candidiasis in Pakistan: clinical characteristics, species distribution and antifungal susceptibility.CRS-MIS in Candida glabrata: sphingolipids modulate echinocandin-Fks interaction.Optimizing Echinocandin dosing and susceptibility breakpoint determination via in vivo pharmacodynamic evaluation against Candida glabrata with and without fks mutations.Two echinocandin-resistant Candida glabrata FKS mutants from South Africa In Vitro Activities of Six Antifungal Drugs Against Candida glabrata Isolates: An Emerging Pathogen.Sequence-identification of Candida species isolated from candidemia.Recurrent episodes of Candidemia due to Candida glabrata, Candida tropicalis and Candida albicans with acquired echinocandin resistance.Fluconazole and Echinocandin Resistance of Candida glabrata Correlates Better with Antifungal Drug Exposure Rather than with MSH2 Mutator Genotype in a French Cohort of Patients Harboring Low Rates of Resistance.Multicenter study of anidulafungin and micafungin MIC distributions and epidemiological cutoff values for eight Candida species and the CLSI M27-A3 broth microdilution method.Current perspectives on echinocandin class drugs.Development of a Luminex-based multiplex assay for detection of mutations conferring resistance to Echinocandins in Candida glabrata.Anidulafungin: when and how? The clinician's view.Molecular fingerprints to identify Candida species.Consensus guidelines for the treatment of yeast infections in the haematology, oncology and intensive care setting, 2014.Nosocomial Candidiasis: Antifungal Stewardship and the Importance of Rapid Diagnosis.Potential Use of MALDI-ToF Mass Spectrometry for Rapid Detection of Antifungal Resistance in the Human Pathogen Candida glabrata Echinocandin resistance and population structure of invasive Candida glabrata isolates from two university hospitals in Germany and Austria.Assessment of caspofungin susceptibility of Candida glabrata by the Etest®, CLSI, and EUCAST methods, and detection of FKS1 and FKS2 mutations.Echinocandins in antifungal pharmacotherapy.Rapid Detection of FKS-Associated Echinocandin Resistance in Candida glabrata Breakthrough candidemia due to multidrug-resistant Candida glabrata during prophylaxis with a low dose of micafungin.Caspofungin for the treatment of immunocompromised and severely ill children and neonates with invasive fungal infections In Vitro Exposure to Increasing Micafungin Concentrations Easily Promotes Echinocandin Resistance in Candida glabrata Isolates.

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P2860

FKS mutations and elevated echinocandin MIC values among Candida glabrata isolates from U.S. population-based surveillance.

http://www.wikidata.org/entity/Q42250085

description

2010 nî lūn-bûn

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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2010年论文

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2010年论文

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name

FKS mutations and elevated ech ...... population-based surveillance.

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FKS mutations and elevated ech ...... population-based surveillance.

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type

label

FKS mutations and elevated ech ...... population-based surveillance.

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FKS mutations and elevated ech ...... population-based surveillance.

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FKS mutations and elevated ech ...... population-based surveillance.

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FKS mutations and elevated ech ...... population-based surveillance.

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Antimicrobial Agents and Chemotherapy

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FKS mutations and elevated ech ...... population-based surveillance.

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P2093

Alicia J Zimbeck

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Angela M Ahlquist

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Lee H Harrison

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Monica M Farley

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Naureen Iqbal

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Tom Chiller

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P2860

Effectiveness of anidulafungin in eradicating Candida species in invasive candidiasis.

MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) Software Version 4.0

Clustal W and Clustal X version 2.0

HyPhy: hypothesis testing using phylogenies

Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study

Epidemiology of invasive candidiasis: a persistent public health problem

Multilocus sequence type analysis reveals both clonality and recombination in populations of Candida glabrata bloodstream isolates from U.S. surveillance studies.

Novel FKS mutations associated with echinocandin resistance in Candida species.

Caspofungin susceptibility testing of isolates from patients with esophageal candidiasis or invasive candidiasis: relationship of MIC to treatment outcome

Specific substitutions in the echinocandin target Fks1p account for reduced susceptibility of rare laboratory and clinical Candida sp. isolates.

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5042-5047

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10.1128/AAC.00836-10

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12

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54

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Shawn R Lockhart

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2010-09-13T00:00:00Z

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20837754

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Candida glabrata

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2981257

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