TNF-alpha mediates diabetes-enhanced chondrocyte apoptosis during fracture healing and stimulates chondrocyte apoptosis through FOXO1. - Wikidata - wikimedia - TriplyDB

TNF-alpha mediates diabetes-enhanced chondrocyte apoptosis during fracture healing and stimulates chondrocyte apoptosis through FOXO1.

TNF-alpha mediates diabetes-enhanced chondrocyte apoptosis during fracture healing and stimulates chondrocyte apoptosis through FOXO1.

http://www.wikidata.org/entity/Q42274273

about

Fracture healing: mechanisms and interventions Diabetes mellitus related bone metabolism and periodontal disease SIRT1 inhibits TNF-α-induced apoptosis of vascular adventitial fibroblasts partly through the deacetylation of FoxO1 FOXO transcription factors: their clinical significance and regulation.FOXO1, TGF-β regulation and wound healing FoxO transcription factors support oxidative stress resistance in human chondrocytes Plasminogen activator inhibitor-1 is involved in impaired bone repair associated with diabetes in female mice.Diabetes reduces mesenchymal stem cells in fracture healing through a TNFα-mediated mechanism FOXO1 differentially regulates both normal and diabetic wound healing.Impaired Fracture Healing Caused by Deficiency of the Immunoreceptor Adaptor Protein DAP12.The convergence of fracture repair and stem cells: interplay of genes, aging, environmental factors and disease.Role of forkhead transcription factors in diabetes-induced oxidative stress.Loss of Bone and Wnt10b Expression in Male Type 1 Diabetic Mice Is Blocked by the Probiotic Lactobacillus reuteri.Augmented LPS responsiveness in type 1 diabetes-derived osteoclasts.Diabetes and Its Effect on Bone and Fracture Healing.Bisphosphonate treatment of type I diabetic mice prevents early bone loss but accentuates suppression of bone formation Low dose aspirin therapy decreases blood glucose levels but does not prevent type i diabetes-induced bone loss Modulation of macrophage activity during fracture repair has differential effects in young adult and elderly mice.Impaired osteogenesis of T1DM bone marrow-derived stromal cells and periosteum-derived cells and their differential in-vitro responses to growth factor rescue.Surgically‑induced mouse models in the study of bone regeneration: Current models and future directions (Review).Review: The diabetic bone: a cellular and molecular perspective.Diabetes and fracture healing: the skeletal effects of diabetic drugs.FoxO1 is crucial for sustaining cardiomyocyte metabolism and cell survival.Diabetes and disordered bone metabolism (diabetic osteodystrophy): time for recognition.Effects of Type 1 Diabetes on Osteoblasts, Osteocytes, and Osteoclasts.Diabetes-induced fibrotic matrix inhibits intramembranous bone healing.Gene expression dynamics during diabetic periodontitis.FOXO1 deletion in keratinocytes improves diabetic wound healing through MMP9 regulation.Chemokine expression is upregulated in chondrocytes in diabetic fracture healing.Delayed bone regeneration and low bone mass in a rat model of insulin-resistant type 2 diabetes mellitus is due to impaired osteoblast function.Apoptosis of periodontium cells in streptozototocin- and ligature-induced experimental diabetic periodontitis in rats.Alcohol-related deficient fracture healing is associated with activation of FoxO transcription factors in mice.Bacterial infection increases periodontal bone loss in diabetic rats through enhanced apoptosis.MiR-29b-3p promotes chondrocyte apoptosis and facilitates the occurrence and development of osteoarthritis by targeting PGRN.Tumor necrosis factor-α antagonist diminishes osteocytic RANKL and sclerostin expression in diabetes rats with periodontitis.Pharmacological rescue of diabetic skeletal stem cell niches.The Impact of Type 2 Diabetes on Bone Fracture Healing.Skeletal fragility in diabetes.The Role of the Immune Cells in Fracture Healing.TNFα contributes to diabetes impaired angiogenesis in fracture healing.

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TNF-alpha mediates diabetes-enhanced chondrocyte apoptosis during fracture healing and stimulates chondrocyte apoptosis through FOXO1.

http://www.wikidata.org/entity/Q42274273

description

2010 nî lūn-bûn

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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2010年论文

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2010年论文

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name

TNF-alpha mediates diabetes-en ...... ocyte apoptosis through FOXO1.

@en

TNF-alpha mediates diabetes-en ...... ocyte apoptosis through FOXO1.

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type

label

TNF-alpha mediates diabetes-en ...... ocyte apoptosis through FOXO1.

@en

TNF-alpha mediates diabetes-en ...... ocyte apoptosis through FOXO1.

@nl

prefLabel

TNF-alpha mediates diabetes-en ...... ocyte apoptosis through FOXO1.

@en

TNF-alpha mediates diabetes-en ...... ocyte apoptosis through FOXO1.

@nl

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Journal of Bone and Mineral Research

P1476

TNF-alpha mediates diabetes-en ...... rocyte apoptosis through FOXO1

@en

P2093

Dan Faibish

http://www.w3.org/2001/XMLSchema#string

Dana T Graves

http://www.w3.org/2001/XMLSchema#string

Jazia Alblowi

http://www.w3.org/2001/XMLSchema#string

Jody McLean

http://www.w3.org/2001/XMLSchema#string

Michelle Siqueira

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Nanarao Krothapalli

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P2860

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Enhanced bone regeneration associated with decreased apoptosis in mice with partial HIF-1alpha deficiency

Tumor necrosis factor alpha (TNF-alpha) coordinately regulates the expression of specific matrix metalloproteinases (MMPS) and angiogenic factors during fracture healing.

Anti-TNF therapy for rheumatoid arthritis and other inflammatory diseases.

Type 2 diabetic mice demonstrate slender long bones with increased fragility secondary to increased osteoclastogenesis.

Diminished bone formation during diabetic fracture healing is related to the premature resorption of cartilage associated with increased osteoclast activity

Tumor necrosis factor-alpha mediates diabetes-enhanced apoptosis of matrix-producing cells and impairs diabetic healing.

A new view of diabetic retinopathy: a neurodegenerative disease of the eye.

Decisions on life and death: FOXO Forkhead transcription factors are in command when PKB/Akt is off duty.

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1604-1615

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10.1002/JBMR.59

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7

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25

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Thomas A Einhorn

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2010-07-01T00:00:00Z

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41722782

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20200974

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3154002

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