Potent and selective inhibition of nitric oxide-sensitive guanylyl cyclase by 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one.
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Inhibition of striatal soluble guanylyl cyclase-cGMP signaling reverses basal ganglia dysfunction and akinesia in experimental parkinsonismCrystal structures of the catalytic domain of human soluble guanylate cyclaseNitric oxide and peroxynitrite in health and diseaseNO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potentialNO-independent regulatory site of direct sGC stimulators like YC-1 and BAY 41-2272Comparison of the properties of the five soluble guanylyl cyclase subunits in Drosophila melanogaster.Low doses of bisphenol A and diethylstilbestrol impair Ca2+ signals in pancreatic alpha-cells through a nonclassical membrane estrogen receptor within intact islets of Langerhans.NCX 4016, a nitric oxide-releasing aspirin, modulates adrenergic vasoconstriction in the perfused rat tail arteryRole of the arginine-nitric oxide pathway in the regulation of vascular smooth muscle cell proliferationInhibition of DNA synthesis in cultured hepatocytes by endotoxin-conditioned medium of activated stellate cells is transforming growth factor-beta and nitric oxide-independentNitric oxide-cGMP pathway facilitates acetylcholine release and bradycardia during vagal nerve stimulation in the guinea-pig in vitroNitric oxide is required for the induction and heterosynaptic spread of long-term potentiation in rat cerebellar slicesNitric oxide and cGMP activate Ca2+-release processes in rat parotid acinar cellsModulation of Kv3 potassium channels expressed in CHO cells by a nitric oxide-activated phosphataseNitric oxide synthase is induced in sporulation of Physarum polycephalumRelaxation to authentic nitric oxide and SIN-1 in rat isolated mesenteric arteries: variable role for smooth muscle hyperpolarizationSpare guanylyl cyclase NO receptors ensure high NO sensitivity in the vascular systemAnandamide elicits an acute release of nitric oxide through endothelial TRPV1 receptor activation in the rat arterial mesenteric bedMobilisation of Ca2+ stores and flagellar regulation in human sperm by S-nitrosylation: a role for NO synthesised in the female reproductive tractDifferential patterning of cGMP in vascular smooth muscle cells revealed by single GFP-linked biosensorsThe Concise Guide to PHARMACOLOGY 2013/14: enzymes.Exquisite sensitivity to subsecond, picomolar nitric oxide transients conferred on cells by guanylyl cyclase-coupled receptors.Effect of nitric oxide donors and noradrenaline on Ca2+ release sites and global intracellular Ca2+ in myocytes from guinea-pig small mesenteric arteries.Cinnamaldehyde and cinnamaldehyde-containing micelles induce relaxation of isolated porcine coronary arteries: role of nitric oxide and calcium.Mechanisms of nitrite reduction to nitric oxide in the heart and vessel wall.iNOS-derived nitric oxide promotes glycolysis by inducing pyruvate kinase M2 nuclear translocation in ovarian cancerAntagonism of soluble guanylyl cyclase attenuates cutaneous vasodilation during whole body heat stress and local warming in humans.The carbon monoxide donor, CORM-2, is an antagonist of ATP-gated, human P2X4 receptors.YC-1 activation of human soluble guanylyl cyclase has both heme-dependent and heme-independent componentsIncreased degradation of MYPT1 contributes to the development of tolerance to nitric oxide in porcine pulmonary artery.Cyclic nucleotide signaling in Toxoplasma gondii bradyzoite differentiation.Nitric oxide down-regulates brain-derived neurotrophic factor secretion in cultured hippocampal neuronsThe antinociceptive effects of JWH-015 in chronic inflammatory pain are produced by nitric oxide-cGMP-PKG-KATP pathway activation mediated by opioidsDual role of endothelial nitric oxide synthase in oxidized LDL-induced, p66Shc-mediated oxidative stress in cultured human endothelial cells.A soluble guanylate cyclase-dependent mechanism is involved in the regulation of net hepatic glucose uptake by nitric oxide in vivo.The anti-aggregating effect of BAY 41-2272, a stimulator of soluble guanylyl cyclase, requires the presence of nitric oxide.The acute antinociceptive effect of HBO₂ is mediated by a NO-cyclic GMP-PKG-KATP channel pathway in mice.Oxygen mediates vascular smooth muscle relaxation in hypoxiaInvolvement of a NO-cyclic GMP-PKG signaling pathway in nitrous oxide-induced antinociception in micePulmonary and systemic vasodilator responses to the soluble guanylyl cyclase activator, BAY 60-2770, are not dependent on endogenous nitric oxide or reduced heme.
P2860
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P2860
Potent and selective inhibition of nitric oxide-sensitive guanylyl cyclase by 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Potent and selective inhibitio ...... iazolo[4,3-a]quinoxalin-1-one.
@en
Potent and selective inhibitio ...... iazolo[4,3-a]quinoxalin-1-one.
@nl
type
label
Potent and selective inhibitio ...... iazolo[4,3-a]quinoxalin-1-one.
@en
Potent and selective inhibitio ...... iazolo[4,3-a]quinoxalin-1-one.
@nl
prefLabel
Potent and selective inhibitio ...... iazolo[4,3-a]quinoxalin-1-one.
@en
Potent and selective inhibitio ...... iazolo[4,3-a]quinoxalin-1-one.
@nl
P2093
P1476
Potent and selective inhibitio ...... iazolo[4,3-a]quinoxalin-1-one.
@en
P2093
P304
P577
1995-08-01T00:00:00Z