scAAV9 intracisternal delivery results in efficient gene transfer to the central nervous system of a feline model of motor neuron disease. - Wikidata - wikimedia - TriplyDB

scAAV9 intracisternal delivery results in efficient gene transfer to the central nervous system of a feline model of motor neuron disease.

scAAV9 intracisternal delivery results in efficient gene transfer to the central nervous system of a feline model of motor neuron disease.

http://www.wikidata.org/entity/Q42288269

about

High resolution MRI anatomy of the cat brain at 3 Tesla.Intracisternal delivery of NFκB-inducible scAAV2/9 reveals locoregional neuroinflammation induced by systemic kainic acid treatment.Widespread and efficient transduction of spinal cord and brain following neonatal AAV injection and potential disease modifying effect in ALS mice.Enzyme replacement in the CSF to treat metachromatic leukodystrophy in mouse model using single intracerebroventricular injection of self-complementary AAV1 vector AAV9-mediated central nervous system-targeted gene delivery via cisterna magna route in mice.Intrathecal administration of AAV/GALC vectors in 10-11-day-old twitcher mice improves survival and is enhanced by bone marrow transplant Plastin-3 extends survival and reduces severity in mouse models of spinal muscular atrophy.Novel Vector Design and Hexosaminidase Variant Enabling Self-Complementary Adeno-Associated Virus for the Treatment of Tay-Sachs Disease.Gene-based therapies of neuromuscular disorders: an update and the pivotal role of patient organizations in their discovery and implementation.Preclinical toxicity evaluation of AAV for pain: evidence from human AAV studies and from the pharmacology of analgesic drugs.Trans-neuronal transduction of spinal neurons following cortical injection and anterograde axonal transport of a bicistronic AAV1 vector Clinical Improvement of Alpha-mannosidosis Cat Following a Single Cisterna Magna Infusion of AAV1.Gene therapy and peripheral nerve repair: a perspective.Intracisternal delivery of AAV9 results in oligodendrocyte and motor neuron transduction in the whole central nervous system of cats.AAV9-NPC1 significantly ameliorates Purkinje cell death and behavioral abnormalities in mouse NPC disease.Long-term neurologic and cardiac correction by intrathecal gene therapy in Pompe disease.Efficient central nervous system AAVrh10-mediated intrathecal gene transfer in adult and neonate rats.Motor Neuron Gene Therapy: Lessons from Spinal Muscular Atrophy for Amyotrophic Lateral Sclerosis.AAV gene delivery to the spinal cord: serotypes, methods, candidate diseases, and clinical trials.Slow Infusion of Recombinant Adeno-Associated Viruses into the Mouse Cerebrospinal Fluid Space.

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scAAV9 intracisternal delivery results in efficient gene transfer to the central nervous system of a feline model of motor neuron disease.

http://www.wikidata.org/entity/Q42288269

description

2013 nî lūn-bûn

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scAAV9 intracisternal delivery ...... model of motor neuron disease.

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scAAV9 intracisternal delivery ...... model of motor neuron disease.

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scAAV9 intracisternal delivery ...... model of motor neuron disease.

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scAAV9 intracisternal delivery ...... model of motor neuron disease.

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scAAV9 intracisternal delivery ...... model of motor neuron disease.

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scAAV9 intracisternal delivery ...... model of motor neuron disease.

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Béatrice Joussemet

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Delphine Briot-Nivard

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John Fyfe

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Laurence Dubreil

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Martine Barkats

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Philippe Moullier

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10.1089/HUM.2012.218

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