E2F1 is a novel fibrogenic gene that regulates cholestatic liver fibrosis through the Egr-1/SHP/EID1 network. - Wikidata - wikimedia - TriplyDB

E2F1 is a novel fibrogenic gene that regulates cholestatic liver fibrosis through the Egr-1/SHP/EID1 network.

E2F1 is a novel fibrogenic gene that regulates cholestatic liver fibrosis through the Egr-1/SHP/EID1 network.

http://www.wikidata.org/entity/Q42289050

about

Nuclear Receptors as Therapeutic Targets in Liver Disease: Are We There Yet?E2F1 inhibits circulating cholesterol clearance by regulating Pcsk9 expression in the liver.Toxicogenomic analysis reveals profibrogenic effects of trichloroethylene in autoimmune-mediated cholangitis in mice Pathobiochemical signatures of cholestatic liver disease in bile duct ligated mice.Rhesus monkey model of liver disease reflecting clinical disease progression and hepatic gene expression analysis.Coding and non-coding gene regulatory networks underlie the immune response in liver cirrhosis.Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21.E2F1 mediates sustained lipogenesis and contributes to hepatic steatosis.Bcl2 is a critical regulator of bile acid homeostasis by dictating Shp and lncRNA H19 function.Pharmacology of bile acid receptors: Evolution of bile acids from simple detergents to complex signaling molecules.Peroxisome proliferator-activated receptor-γ agonist inhibits collagen synthesis in human keloid fibroblasts by suppression of early growth response-1 expression through upregulation of miR-543 expression.Intestine-specific homeobox (ISX) upregulates E2F1 expression and related oncogenic activities in HCC.The Spectrum of E2F in Liver Disease--Mediated Regulation in Biology and Cancer.Growth factor receptor binding protein 14 inhibition triggers insulin-induced mouse hepatocyte proliferation and is associated with hepatocellular carcinoma.REV-ERBα Activates C/EBP Homologous Protein to Control Small Heterodimer Partner-Mediated Oscillation of Alcoholic Fatty Liver.A Novel Small Molecule Activator of Nuclear Receptor SHP Inhibits HCC Cell Migration via Suppressing Ccl2.Epigallocatechin gallate inhibits hepatitis B virus via farnesoid X receptor alpha.Molecular profiling of dilated cardiomyopathy that progresses to heart failure.Interactions Between Nuclear Receptor SHP and FOXA1 Maintain Oscillatory Homocysteine Homeostasis in Mice.H19 promotes cholestatic liver fibrosis by preventing ZEB1-mediated inhibition of epithelial cell adhesion molecule.Arsenic silences hepatic PDK4 expression through activation of histone H3K9 methylatransferase G9a Dynamic transcription factor activity networks in response to independently altered mechanical and adhesive microenvironmental cues Loss of miR-141/200c ameliorates hepatic steatosis and inflammation by reprogramming multiple signaling pathways in NASH.The indole derivative NecroX-7 improves nonalcoholic steatohepatitis in ob/ob mice through suppression of mitochondrial ROS/RNS and inflammation.Computational identification of microRNAs and their targets in liver cirrhosis.E2F1, a Novel Regulator of Metabolism.lncRNA H19 interacts with polypyrimidine tract-binding protein 1 to reprogram hepatic lipid homeostasis.Metabolomics Analysis Revealed Distinct Cyclic Changes of Metabolites Altered by Chronic Ethanol-Plus-Binge and Shp Deficiency.Long noncoding RNA MEG3 induces cholestatic liver injury by interaction with PTBP1 to facilitate shp mRNA decay.Hepatocyte nuclear receptor SHP suppresses inflammation and fibrosis in a mouse model of nonalcoholic steatohepatitis.High-mobility-group protein 2 regulated by microRNA-127 and small heterodimer partner modulates pluripotency of mouse embryonic stem cells and liver tumor initiating cells.LncRNA AK054921 and AK128652 are potential serum biomarkers and predictors of patient survival with alcoholic cirrhosis.Targeting Liver Cancer and Associated Pathologies in Mice with a Mitochondrial VDAC1-Based Peptide.Bile acid metabolism and signaling in liver disease and therapy H19 Is Expressed in Hybrid Hepatocyte Nuclear Factor 4α Periportal Hepatocytes but Not Cytokeratin 19 Cholangiocytes in Cholestatic Livers

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P2860

E2F1 is a novel fibrogenic gene that regulates cholestatic liver fibrosis through the Egr-1/SHP/EID1 network.

http://www.wikidata.org/entity/Q42289050

description

2014 nî lūn-bûn

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2014年の論文

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name

E2F1 is a novel fibrogenic gen ...... gh the Egr-1/SHP/EID1 network.

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E2F1 is a novel fibrogenic gen ...... gh the Egr-1/SHP/EID1 network.

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E2F1 is a novel fibrogenic gen ...... gh the Egr-1/SHP/EID1 network.

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E2F1 is a novel fibrogenic gen ...... gh the Egr-1/SHP/EID1 network.

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prefLabel

E2F1 is a novel fibrogenic gen ...... gh the Egr-1/SHP/EID1 network.

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E2F1 is a novel fibrogenic gen ...... gh the Egr-1/SHP/EID1 network.

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E2F1 is a novel fibrogenic gen ...... gh the Egr-1/SHP/EID1 network.

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Bo Kong

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Bryan Copple

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Grace L Guo

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Jun Xu

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Li Wang

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Ningyi Xu

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Yuxia Zhang

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P2860

A transcriptional inhibitor targeted by the atypical orphan nuclear receptor SHP

Mechanisms of hepatic fibrogenesis

Role of nuclear receptor SHP in metabolism and cancer.

A new xenobiotic-induced mouse model of sclerosing cholangitis and biliary fibrosis

Upregulation of early growth response factor-1 by bile acids requires mitogen-activated protein kinase signaling.

Nuclear receptor SHP, a death receptor that targets mitochondria, induces apoptosis and inhibits tumor growth.

Role of nuclear receptors in the adaptive response to bile acids and cholestasis: pathogenetic and therapeutic considerations.

Viral-mediated noisy gene expression reveals biphasic E2f1 response to MYC

Transcriptional regulation of hepatic stellate cell activation

Bile acids induce inflammatory genes in hepatocytes: a novel mechanism of inflammation during obstructive cholestasis.

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919-930

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