Efficient targeted DNA methylation with chimeric dCas9-Dnmt3a-Dnmt3L methyltransferase. - Wikidata - wikimedia - TriplyDB

Efficient targeted DNA methylation with chimeric dCas9-Dnmt3a-Dnmt3L methyltransferase.

Efficient targeted DNA methylation with chimeric dCas9-Dnmt3a-Dnmt3L methyltransferase.

http://www.wikidata.org/entity/Q42291815

about

DNA Methylation Dynamics and Cocaine in the Brain: Progress and Prospects.Understanding RNA modifications: the promises and technological bottlenecks of the 'epitranscriptome'.Targeted DNA methylation in vivo using an engineered dCas9-MQ1 fusion protein.Advanced Gene Manipulation Methods for Stem Cell Theranostics.Targeted epigenetic editing of SPDEF reduces mucus production in lung epithelial cells.Neuronal DNA Methyltransferases: Epigenetic Mediators between Synaptic Activity and Gene Expression?Targeted DNA methylation in human cells using engineered dCas9-methyltransferases.DNA epigenome editing using CRISPR-Cas SunTag-directed DNMT3A.dCas9-based epigenome editing suggests acquisition of histone methylation is not sufficient for target gene repression.Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors.A CRISPR reimagining: New twists and turns of CRISPR beyond the genome-engineering revolution.Target specificity of mammalian DNA methylation and demethylation machinery.Genome-wide tracking of dCas9-methyltransferase footprints.Harnessing natural DNA modifying activities for editing of the genome and epigenome.The DNA methyltransferase family: a versatile toolkit for epigenetic regulation.Epigenetic editing: How cutting-edge targeted epigenetic modification might provide novel avenues for autoimmune disease therapy.Designing Epigenome Editors: Considerations of Biochemical and Locus Specificities.Applications of CRISPR/Cas9 in the Mammalian Central Nervous System.Genome-wide determination of on-target and off-target characteristics for RNA-guided DNA methylation by dCas9 methyltransferases.The CRISPR tool kit for genome editing and beyond.Protein Engineering Strategies to Expand CRISPR-Cas9 Applications Experience-dependent neuroplasticity of the developing hypothalamus: integrative epigenomic approaches A modular dCas9-SunTag DNMT3A epigenome editing system overcomes pervasive off-target activity of direct fusion dCas9-DNMT3A constructs Comprehensive Analysis of Gene Expression Profiles and DNA Methylome reveals Oas1, Ppie, Polr2g as Pathogenic Target Genes of Gestational Diabetes Mellitus CRISPR-based reagents to study the influence of the epigenome on gene expression

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Efficient targeted DNA methylation with chimeric dCas9-Dnmt3a-Dnmt3L methyltransferase.

http://www.wikidata.org/entity/Q42291815

description

2016 nî lūn-bûn

@nan

2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

2016年论文

@zh

2016年论文

@zh-cn

name

Efficient targeted DNA methylation with chimeric dCas9-Dnmt3a-Dnmt3L methyltransferase.

@en

Efficient targeted DNA methylation with chimeric dCas9-Dnmt3a-Dnmt3L methyltransferase.

@nl

type

label

Efficient targeted DNA methylation with chimeric dCas9-Dnmt3a-Dnmt3L methyltransferase.

@en

Efficient targeted DNA methylation with chimeric dCas9-Dnmt3a-Dnmt3L methyltransferase.

@nl

prefLabel

Efficient targeted DNA methylation with chimeric dCas9-Dnmt3a-Dnmt3L methyltransferase.

@en

Efficient targeted DNA methylation with chimeric dCas9-Dnmt3a-Dnmt3L methyltransferase.

@nl

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Nucleic Acids Research

P1476

Efficient targeted DNA methylation with chimeric dCas9-Dnmt3a-Dnmt3L methyltransferase.

@en

P2093

Albert Jeltsch

http://www.w3.org/2001/XMLSchema#string

Goran Kungulovski

http://www.w3.org/2001/XMLSchema#string

Renata Z Jurkowska

http://www.w3.org/2001/XMLSchema#string

Tamir Chandra

http://www.w3.org/2001/XMLSchema#string

P2860

The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1

The DNA methyltransferase-like protein DNMT3L stimulates de novo methylation by Dnmt3a

RNA-guided human genome engineering via Cas9

CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

Chromatin regulation at the frontier of synthetic biology

Functions of DNA methylation: islands, start sites, gene bodies and beyond

Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression

CRISPR RNA-guided activation of endogenous human genes

Targeted methylation of the epithelial cell adhesion molecule (EpCAM) promoter to silence its expression in ovarian cancer cells

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1703-1713

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scholarly article

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10.1093/NAR/GKW1112

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4

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45

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Tomasz Jurkowski

Richard Reinhardt

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2016-11-29T00:00:00Z

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27899645

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DNA methylation

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5389507

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