Rewiring yeast acetate metabolism through MPC1 loss of function leads to mitochondrial damage and decreases chronological lifespan

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During yeast chronological aging resveratrol supplementation results in a short-lived phenotype Sir2-dependent.The role of autophagy in the regulation of yeast life span.

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Rewiring yeast acetate metabolism through MPC1 loss of function leads to mitochondrial damage and decreases chronological lifespan

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Rewiring yeast acetate metabol ...... creases chronological lifespan

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Rewiring yeast acetate metabol ...... creases chronological lifespan

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Rewiring yeast acetate metabol ...... creases chronological lifespan

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Rewiring yeast acetate metabol ...... creases chronological lifespan

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Rewiring yeast acetate metabol ...... creases chronological lifespan

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Rewiring yeast acetate metabol ...... creases chronological lifespan

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Rewiring yeast acetate metabol ...... creases chronological lifespan

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Damiano Pellegrino Coppola

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Ivan Orlandi

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Marina Vai

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P2860

Extending healthy life span--from yeast to humans

The search for antiaging interventions: from elixirs to fasting regimens

Carnitine-dependent metabolic activities in Saccharomyces cerevisiae: three carnitine acetyltransferases are essential in a carnitine-dependent strain.

A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans.

Sir2 blocks extreme life-span extension.

Molecular characterization of carnitine-dependent transport of acetyl-CoA from peroxisomes to mitochondria in Saccharomyces cerevisiae and identification of a plasma membrane carnitine transporter, Agp2p.

Overproduction of acetyl-coenzyme A synthetase isoenzymes in respiring Saccharomyces cerevisiae cells does not reduce acetate production after exposure to glucose excess.

Engineering of the pyruvate dehydrogenase bypass in Saccharomyces cerevisiae: role of the cytosolic Mg(2+) and mitochondrial K(+) acetaldehyde dehydrogenases Ald6p and Ald4p in acetate formation during alcoholic fermentation

Functional analysis of the ALD gene family of Saccharomyces cerevisiae during anaerobic growth on glucose: the NADP+-dependent Ald6p and Ald5p isoforms play a major role in acetate formation.

Identification and functional expression of the mitochondrial pyruvate carrier.

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393-405

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scholarly article

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10.15698/MIC2014.12.178

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2014-11-18T00:00:00Z

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269703915

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5349135

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Rewiring yeast acetate metabolism through MPC1 loss of function leads to mitochondrial damage and decreases chronological lifespan

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P2860

P2860

Rewiring yeast acetate metabolism through MPC1 loss of function leads to mitochondrial damage and decreases chronological lifespan

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P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P5875

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P5875

P698

P932