Topoisomerase I (Top1): a major target of FL118 for its antitumor efficacy or mainly involved in its side effects of hematopoietic toxicity?
about
Camptothecin (CPT) and its derivatives are known to target topoisomerase I (Top1) as their mechanism of action: did we miss something in CPT analogue molecular targets for treating human disease such as cancer?Camptothecin exhibits topoisomerase1-independent KMT1A suppression and myogenic differentiation in alveolar rhabdomyosarcoma cells.
P2860
Topoisomerase I (Top1): a major target of FL118 for its antitumor efficacy or mainly involved in its side effects of hematopoietic toxicity?
description
2017 nî lūn-bûn
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2017年の論文
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name
Topoisomerase I (Top1): a majo ...... cts of hematopoietic toxicity?
@en
type
label
Topoisomerase I (Top1): a majo ...... cts of hematopoietic toxicity?
@en
prefLabel
Topoisomerase I (Top1): a majo ...... cts of hematopoietic toxicity?
@en
P2093
P2860
P1476
Topoisomerase I (Top1): a majo ...... cts of hematopoietic toxicity?
@en
P2093
Chunyang Jin
Danni L Harris
David Westover
Fengzhi Li
Guohui Jiang
Jianqun Liao
Patrick M Boland
Xiang Ling
Yuping Wang
P2860
P304
P577
2017-02-01T00:00:00Z