Live-cell imaging evidence for the ciliary transport of rod photoreceptor opsin by heterotrimeric kinesin-2.
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Molecular complexes that direct rhodopsin transport to primary ciliaHow do cilia organize signalling cascades?Kinesin-2 family motors in the unusual photoreceptor ciliumIntraflagellar transport complex structure and cargo interactions.The roles of evolutionarily conserved functional modules in cilia-related trafficking.The Arf and Rab11 effector FIP3 acts synergistically with ASAP1 to direct Rabin8 in ciliary receptor targetingmyosin 7aa(-/-) mutant zebrafish show mild photoreceptor degeneration and reduced electroretinographic responses.Analysis of KIF17 distal tip trafficking in zebrafish cone photoreceptors.Diverse cell type-specific mechanisms localize G protein-coupled receptors to Caenorhabditis elegans sensory ciliaRetrograde intraciliary trafficking of opsin during the maintenance of cone-shaped photoreceptor outer segments of Xenopus laevis.Impact of reduced rhodopsin expression on the structure of rod outer segment disc membranesHeterotrimeric kinesin-2 (KIF3) mediates transition zone and axoneme formation of mouse photoreceptorsRod disc renewal occurs by evagination of the ciliary plasma membrane that makes cadherin-based contacts with the inner segment.A FRAP-Based Method for Monitoring Molecular Transport in Ciliary Photoreceptor Cells In Vivo.Photoreceptors at a glance.Unexpected Roles for Ciliary Kinesins and Intraflagellar Transport Proteins.Signals governing the trafficking and mistrafficking of a ciliary GPCR, rhodopsin.Protein sorting, targeting and trafficking in photoreceptor cellsBiochemical analysis of a rhodopsin photoactivatable GFP fusion as a model of G-protein coupled receptor transport.An unconventional secretory pathway mediates the cilia targeting of peripherin/rdsUntangling ciliary access and enrichment of two rhodopsin-like receptors using quantitative fluorescence microscopy reveals cell-specific sorting pathways.Molecular basis for photoreceptor outer segment architecture.Intraflagellar transport: mechanisms of motor action, cooperation, and cargo delivery.Photoreceptor outer segment as a sink for membrane proteins: hypothesis and implications in retinal ciliopathies.Regulated membrane protein entry into flagella is facilitated by cytoplasmic microtubules and does not require IFT.The cytoplasmic tail of rhodopsin triggers rapid rod degeneration in kinesin-2 mutants.Functional differentiation of cooperating kinesin-2 motors orchestrates cargo import and transport in C. elegans cilia.Abnormal photoreceptor outer segment development and early retinal degeneration in kif3a mutant zebrafish.Maintaining centrosomes and cilia.The Arf GEF GBF1 and Arf4 synergize with the sensory receptor cargo, rhodopsin, to regulate ciliary membrane trafficking.Intraflagellar transport velocity is governed by the number of active KIF17 and KIF3AB motors and their motility properties under load.C2orf71a/pcare1 is important for photoreceptor outer segment morphogenesis and visual function in zebrafish.
P2860
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P2860
Live-cell imaging evidence for the ciliary transport of rod photoreceptor opsin by heterotrimeric kinesin-2.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Live-cell imaging evidence for ...... n by heterotrimeric kinesin-2.
@en
Live-cell imaging evidence for ...... n by heterotrimeric kinesin-2.
@nl
type
label
Live-cell imaging evidence for ...... n by heterotrimeric kinesin-2.
@en
Live-cell imaging evidence for ...... n by heterotrimeric kinesin-2.
@nl
prefLabel
Live-cell imaging evidence for ...... n by heterotrimeric kinesin-2.
@en
Live-cell imaging evidence for ...... n by heterotrimeric kinesin-2.
@nl
P2093
P2860
P1476
Live-cell imaging evidence for ...... n by heterotrimeric kinesin-2.
@en
P2093
Carrie M Louie
David S Williams
Emilie Colin
P2860
P304
10587-10593
P356
10.1523/JNEUROSCI.0015-12.2012
P407
P577
2012-08-01T00:00:00Z