NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer. - Wikidata - wikimedia - TriplyDB

NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer.

NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer.

http://www.wikidata.org/entity/Q42330675

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Antioxidant Activity during Tumor Progression: A Necessity for the Survival of Cancer Cells?Anti-oxidative effects of 4-hydroxybenzyl alcohol in astrocytes confer protective effects in autocrine and paracrine manners.Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism Oxidative Stress, Nrf2, and Epigenetic Modification Contribute to Anticancer Drug Resistance.Enhancer Reprogramming Promotes Pancreatic Cancer Metastasis.Challenges and Opportunities in Modeling Pancreatic Cancer.Controversy about pharmacological modulation of Nrf2 for cancer therapy Targeting reactive oxygen species in development and progression of pancreatic cancer.ROS in Cancer: The Burning Question.RAS Proteins and Their Regulators in Human Disease.Role of ADAM10 in intestinal crypt homeostasis and tumorigenesis.Critical Contribution of Nuclear Factor Erythroid 2-related Factor 2 (NRF2) to Electrophile-induced Interleukin-11 Production.NRF2: Translating the Redox Code.Superoxide Dismutases in Pancreatic Cancer.ROS in translation: Chink in the armor KEAP1 loss modulates sensitivity to kinase targeted therapy in lung cancer.Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis.Transcriptional Regulation by Nrf2.NRF2 Is a Major Target of ARF in p53-Independent Tumor Suppression.CDK20 interacts with KEAP1 to activate NRF2 and promotes radiochemoresistance in lung cancer cells.Cancer, Oxidative Stress, and Metastasis.Functional analysis of a CDKN2A 5'UTR germline variant associated with pancreatic cancer development.Proteome Stability as a Key Factor of Genome Integrity.Chemical Proteomics Identifies Druggable Vulnerabilities in a Genetically Defined Cancer.The A to Z of modulated cell patterning by mammalian thioredoxin reductases.Nrf2 promotes mutant K-ras/p53-driven pancreatic carcinogenesis.Systems Biology Approaches to Redox Metabolism in Stress and Disease States.Differential Response of Glioma Stem Cells to Arsenic Trioxide Therapy Is Regulated by MNK1 and mRNA Translation.Repurposing of the CDK inhibitor PHA-767491 as a NRF2 inhibitor drug candidate for cancer therapy via redox modulation.IKKα inactivation promotes Kras-initiated lung adenocarcinoma development through disrupting major redox regulatory pathways.Targeting Metabolism for Cancer Therapy.Simultaneous K-ras activation and Keap1 deletion cause atrophy of pancreatic parenchyma.Synthetic Lethal Vulnerabilities in KRAS-Mutant Cancers.Cellular senescence in gastrointestinal diseases: from pathogenesis to therapeutics.Pharmacogenomics of chemically distinct classes of Keap1-Nrf2 activators identify common and unique gene, protein, and pathway responses in vivo.NRF2 Addiction in Cancer Cells.TUMOR CROSSTALK NETWORKS PROMOTE GROWTH AND SUPPORT IMMUNE EVASION IN PANCREATIC CANCER.Colorectal Tumors Require NUAK1 for Protection from Oxidative Stress.Pancreas 3D Organoids: Current and Future Aspects as a Research Platform for Personalized Medicine in Pancreatic Cancer.Cancer: Double trouble for tumours.

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P2860

NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer.

http://www.wikidata.org/entity/Q42330675

description

2016 nî lūn-bûn

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年论文

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2016年论文

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2016年论文

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name

NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer.

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NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer.

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type

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NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer.

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NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer.

@nl

prefLabel

NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer.

@en

NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer.

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J.CELL.2016.06.056

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NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer.

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Brandon Da Silva

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Christina Schoepfer

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Craig B Thompson

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Daniel Öhlund

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Darryl J Pappin

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Edward E Schmidt

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Eun Jung Lee

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Howard C Crawford

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Iok In Christine Chio

http://www.w3.org/2001/XMLSchema#string

John Erby Wilkinson

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P2860

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation

First-in-man clinical trial of the oral pan-AKT inhibitor MK-2206 in patients with advanced solid tumors.

Cancer statistics, 2015

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

Regulation of translation initiation in eukaryotes: mechanisms and biological targets

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

Nrf2 protein up-regulates antiapoptotic protein Bcl-2 and prevents cellular apoptosis

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963-976

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10.1016/J.CELL.2016.06.056

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166

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Gina M DeNicola

Mariano Ponz-Sarvise

Seyed Mehdi Jafarnejad

Nahum Sonenberg

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2016-07-27T00:00:00Z

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27477511

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