Sphingosine kinase 2 and multiple myeloma

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The Role of Sphingosine-1-Phosphate and Ceramide-1-Phosphate in Inflammation and Cancer.

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Sphingosine kinase 2 and multiple myeloma

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2017 nî lūn-bûn

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2017年の論文

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2017年論文

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2017年論文

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2017年論文

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2017年論文

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2017年论文

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2017年论文

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Sphingosine kinase 2 and multiple myeloma

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Sphingosine kinase 2 and multiple myeloma

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Sphingosine kinase 2 and multiple myeloma

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Sphingosine kinase 2 and multiple myeloma

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Sphingosine kinase 2 and multiple myeloma

@en

Sphingosine kinase 2 and multiple myeloma

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Sphingosine kinase 2 and multiple myeloma

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Nigel J Pyne

http://www.w3.org/2001/XMLSchema#string

Susan Pyne

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Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate.

Inhibition of sphingosine kinase 2 downregulates the expression of c-Myc and Mcl-1 and induces apoptosis in multiple myeloma.

Assessment of the effect of sphingosine kinase inhibitors on apoptosis,unfolded protein response and autophagy of T-cell acute lymphoblastic leukemia cells; indications for novel therapeutics.

Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation.

The Sphingosine Kinase 2 Inhibitor ABC294640 Reduces the Growth of Prostate Cancer Cells and Results in Accumulation of Dihydroceramides In Vitro and In Vivo.

Membrane lipid saturation activates endoplasmic reticulum unfolded protein response transducers through their transmembrane domains

Sphingosine kinase 2 inhibition synergises with bortezomib to target myeloma by enhancing endoplasmic reticulum stress.

Proteasomal degradation of sphingosine kinase 1 and inhibition of dihydroceramide desaturase by the sphingosine kinase inhibitors, SKi or ABC294640, induces growth arrest in androgen-independent LNCaP-AI prostate cancer cells.

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43596-43597

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scholarly article

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10.18632/ONCOTARGET.17420

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English

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2017-04-25T00:00:00Z

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28455955

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5546425

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Sphingosine kinase 2 and multiple myeloma

about

P2860

P2860

Sphingosine kinase 2 and multiple myeloma

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P698

P932