HSPB1 facilitates ERK-mediated phosphorylation and degradation of BIM to attenuate endoplasmic reticulum stress-induced apoptosis.

about

The irreversible ERBB1/2/4 inhibitor neratinib interacts with the BCL-2 inhibitor venetoclax to kill mammary cancer cells.The small heat shock protein HSPB1 protects mice from sepsis

P2860

Q50047476-8B545523-0A1C-453E-9191-96921B39276A Q58730897-0935A812-5B49-45C8-AF4C-6063DEB2392D

P2860

HSPB1 facilitates ERK-mediated phosphorylation and degradation of BIM to attenuate endoplasmic reticulum stress-induced apoptosis.

Item

http://www.wikidata.org/entity/Q42358226

description

2017 nî lūn-bûn

@nan

2017年の論文

@ja

2017年論文

@yue

2017年論文

@zh-hant

2017年論文

@zh-hk

2017年論文

@zh-mo

2017年論文

@zh-tw

2017年论文

@wuu

2017年论文

@zh

2017年论文

@zh-cn

name

HSPB1 facilitates ERK-mediated ...... ulum stress-induced apoptosis.

@en

HSPB1 facilitates ERK-mediated ...... ulum stress-induced apoptosis.

@nl

type

Item

label

HSPB1 facilitates ERK-mediated ...... ulum stress-induced apoptosis.

@en

HSPB1 facilitates ERK-mediated ...... ulum stress-induced apoptosis.

@nl

prefLabel

HSPB1 facilitates ERK-mediated ...... ulum stress-induced apoptosis.

@en

HSPB1 facilitates ERK-mediated ...... ulum stress-induced apoptosis.

@nl

P1476

HSPB1 facilitates ERK-mediated ...... culum stress-induced apoptosis

@en

P2093

Deepu Oommen

http://www.w3.org/2001/XMLSchema#string

Donna Kennedy

http://www.w3.org/2001/XMLSchema#string

Michiel Krols

http://www.w3.org/2001/XMLSchema#string

Reka Chakravarthy

http://www.w3.org/2001/XMLSchema#string

Sanjeev Gupta

http://www.w3.org/2001/XMLSchema#string

Sophie Janssens

http://www.w3.org/2001/XMLSchema#string

Svetlana Saveljeva

http://www.w3.org/2001/XMLSchema#string

Vincent Timmerman

http://www.w3.org/2001/XMLSchema#string

P2860

HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1alpha-XBP1 signaling through a physical interaction

The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets

ERK1/2-dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl-1 and Bcl-xL

Hsp27 as a negative regulator of cytochrome C release.

Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes

HSP27 is a ubiquitin-binding protein involved in I-kappaBalpha proteasomal degradation

Regulation of Bim in Health and Disease

Increased monomerization of mutant HSPB1 leads to protein hyperactivity in Charcot-Marie-Tooth neuropathy

The deubiquitinase Usp27x stabilizes the BH3-only protein Bim and enhances apoptosis

Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress/tumor necrosis factor alpha by phosphorylation

P304

e3026

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/CDDIS.2017.408

http://www.w3.org/2001/XMLSchema#string

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Leonardo Almeida-Souza

P577

2017-08-31T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

29048431

http://www.w3.org/2001/XMLSchema#string

P921

phosphorylation

endoplasmic reticulum

P932

5596589

http://www.w3.org/2001/XMLSchema#string

HSPB1 facilitates ERK-mediated phosphorylation and degradation of BIM to attenuate endoplasmic reticulum stress-induced apoptosis.

about

P2860

P2860

HSPB1 facilitates ERK-mediated phosphorylation and degradation of BIM to attenuate endoplasmic reticulum stress-induced apoptosis.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P921

P932