Towards selective pharmacological modulation of protein kinase C--opportunities for the development of novel antineoplastic agents
about
Phorbol 12-myristate 13-acetate induces protein kinase ceta-specific proliferative response in astrocytic tumor cellsPKC-eta mediates glioblastoma cell proliferation through the Akt and mTOR signaling pathways.Efficacy and toxicity of the antisense oligonucleotide aprinocarsen directed against protein kinase C-alpha delivered as a 21-day continuous intravenous infusion in patients with recurrent high-grade astrocytomas.Update on pulmonary edema: the role and regulation of endothelial barrier function.Angiotropic metastatic malignant melanoma in a canine mammary glandProtein kinase C alpha expression in breast and ovarian cancer.Moving the Frontiers of Cancer Chemotherapy for Solid Tumors by Changing the Scope of Drug Development.Review of survival analyses published in cancer journalsA phase I trial of bryostatin 1 in patients with advanced malignancy using a 24 hour intravenous infusion.Bryostatin 1-tamoxifen combinations show synergistic effects on the inhibition of growth of P388 cells in vitro.The role of protein kinase C-alpha in hematologic malignancies.Isoenzymes of protein kinase C: differential involvement in apoptosis and pathogenesisInduction of cell death by stimulation of protein kinase C in human epithelial cells expressing a mutant ras oncogene: a potential therapeutic targetProtein kinase C: a family of isoenzymes with distinct roles in pathogenesis.Staurosporine increases carcinoembryonic antigen expression in a human colon cancer cell line.Establishment of a murine leukaemia cell line resistant to the growth-inhibitory effect of bryostatin 1Toxicity of phorbol esters for human epithelial cells expressing a mutant ras oncogene.Early response gene signalling in bryostatin-stimulated primary B chronic lymphocytic leukaemia cells in vitro.Covalent modification of protein kinase C isozymes by the inactivating peptide substrate analog N-biotinyl-Arg-Arg-Arg-Cys-Leu-Arg-Arg-Leu. Evidence that the biotinylated peptide is an active-site affinity label.
P2860
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P2860
Towards selective pharmacological modulation of protein kinase C--opportunities for the development of novel antineoplastic agents
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Towards selective pharmacologi ...... of novel antineoplastic agents
@en
Towards selective pharmacologi ...... of novel antineoplastic agents
@nl
type
label
Towards selective pharmacologi ...... of novel antineoplastic agents
@en
Towards selective pharmacologi ...... of novel antineoplastic agents
@nl
prefLabel
Towards selective pharmacologi ...... of novel antineoplastic agents
@en
Towards selective pharmacologi ...... of novel antineoplastic agents
@nl
P2860
P31
P356
P1476
Towards selective pharmacologi ...... of novel antineoplastic agents
@en
P2093
P2860
P2888
P356
10.1038/BJC.1992.209
P407
P577
1992-07-01T00:00:00Z