Membrane-interactive lipids as experimental anticancer drugs.
about
MDR1 causes resistance to the antitumour drug miltefosineAlkylphosphocholines and Alkylphosphocholine LiposomesPhospholipid antitumor agents.Evaluation of in vitro and in vivo anti-inflammatory activity of biologically active phospholipids with anti-neoplastic potential in porcine model.The ether lipid ET-18-OCH3 increases cytosolic Ca2+ concentrations in Madin Darby canine kidney cellsIn vitro antitumour activity of the novel imidazoisoquinoline SDZ 62-434.Resistance to the new anti-cancer phospholipid ilmofosine (BM 41 440)1-O-octadecyl-2-O-methyl-glycerophosphocholine inhibits the transduction of growth signals via the MAPK cascade in cultured MCF-7 cells.Structure-activity relationships of glucosamine-derived glycerolipids: the role of the anomeric linkage, the cationic charge and the glycero moiety on the antitumor activity.Synthesis and antitumor activity of ether glycerophospholipids bearing a carbamate moiety at the sn-2 position: selective sensitivity against prostate cancer cell lines.Leishmania donovani resistance to miltefosine involves a defective inward translocation of the drug.A glycosylated antitumor ether lipid kills cells via paraptosis-like cell death.Downregulation of Apaf-1 and caspase-3 by RNA interference in human glioma cells: consequences for erucylphosphocholine-induced apoptosis.Structure-dependent effects of glucose-containing analogs of platelet activating factor (PAF) on membrane integrity.Lysophosphatidylcholine and 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine inhibit the CDP-choline pathway of phosphatidylcholine synthesis at the CTP:phosphocholine cytidylyltransferase step.The induction of apoptosis is a common feature of the cytotoxic action of ether-linked glycerophospholipids in human leukemic cells.Cytostatic activity of new synthetic anti-tumor aza-alkyllysophospholipids.Growth arrest vs direct cytotoxicity and the importance of molecular structure for the in vitro anti-tumour activity of ether lipids.Alkyl lysophospholipids inhibit phorbol ester-stimulated phospholipase D activity and DNA synthesis in fibroblasts.Upregulation of cell cycle genes in head and neck cancer patients may be antagonized by erufosine's down regulation of cell cycle processes in OSCC cells.
P2860
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P2860
Membrane-interactive lipids as experimental anticancer drugs.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Membrane-interactive lipids as experimental anticancer drugs.
@en
Membrane-interactive lipids as experimental anticancer drugs.
@nl
type
label
Membrane-interactive lipids as experimental anticancer drugs.
@en
Membrane-interactive lipids as experimental anticancer drugs.
@nl
prefLabel
Membrane-interactive lipids as experimental anticancer drugs.
@en
Membrane-interactive lipids as experimental anticancer drugs.
@nl
P2860
P31
P921
P356
P1476
Membrane-interactive lipids as experimental anticancer drugs.
@en
P2093
P2860
P2888
P304
P356
10.1038/BJC.1991.277
P407
P577
1991-08-01T00:00:00Z
P5875
P6179
1008140916