Selective AKT Inhibition by MK-2206 Represses Colorectal Cancer-Initiating Stem Cells.

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AGO2 involves the malignant phenotypes and FAK/PI3K/AKT signaling pathway in hypopharyngeal-derived FaDu cells.Downregulated Tim-3 expression is responsible for the incidence and development of colorectal cancer.PIK3CA mutations confer resistance to first-line chemotherapy in colorectal cancer.

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Selective AKT Inhibition by MK-2206 Represses Colorectal Cancer-Initiating Stem Cells.

Item

http://www.wikidata.org/entity/Q42381878

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2016 nî lūn-bûn

@nan

2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

2016年论文

@zh

2016年论文

@zh-cn

name

Selective AKT Inhibition by MK-2206 Represses Colorectal Cancer-Initiating Stem Cells.

@en

Selective AKT Inhibition by MK-2206 Represses Colorectal Cancer-Initiating Stem Cells.

@nl

type

Item

label

Selective AKT Inhibition by MK-2206 Represses Colorectal Cancer-Initiating Stem Cells.

@en

Selective AKT Inhibition by MK-2206 Represses Colorectal Cancer-Initiating Stem Cells.

@nl

prefLabel

Selective AKT Inhibition by MK-2206 Represses Colorectal Cancer-Initiating Stem Cells.

@en

Selective AKT Inhibition by MK-2206 Represses Colorectal Cancer-Initiating Stem Cells.

@nl

P1476

Selective AKT Inhibition by MK-2206 Represses Colorectal Cancer-Initiating Stem Cells

@en

P2093

Alexander Luetticke

http://www.w3.org/2001/XMLSchema#string

Elsie Oppermann

http://www.w3.org/2001/XMLSchema#string

Ilaria Lunger

http://www.w3.org/2001/XMLSchema#string

Katharina Holzer

http://www.w3.org/2001/XMLSchema#string

Nadine Haetscher

http://www.w3.org/2001/XMLSchema#string

Patrizia Malkomes

http://www.w3.org/2001/XMLSchema#string

P2860

Global cancer statistics

Cancer treatment and survivorship statistics, 2012

First-in-man clinical trial of the oral pan-AKT inhibitor MK-2206 in patients with advanced solid tumors.

Identification and expansion of human colon-cancer-initiating cells

A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis.

Novel expression patterns of PI3K/Akt/mTOR signaling pathway components in colorectal cancer.

Antitumor activities of ATP-competitive inhibitors of mTOR in colon cancer cells.

Inhibition of AKT with the orally active allosteric AKT inhibitor, MK-2206, sensitizes endometrial cancer cells to progestin.

The Akt-specific inhibitor MK2206 selectively inhibits thyroid cancer cells harboring mutations that can activate the PI3K/Akt pathway.

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s10434-016-5218-z

P304

2849-2857

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scholarly article

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10.1245/S10434-016-5218-Z

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Wolf Otto Bechstein

Michael A Rieger

Hubert Serve

P577

2016-04-08T00:00:00Z

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P5875

300082381

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P6179

1049232986

http://www.w3.org/2001/XMLSchema#string

P698

27059026

http://www.w3.org/2001/XMLSchema#string

P921

colorectal cancer

P932

4972858

http://www.w3.org/2001/XMLSchema#string

Selective AKT Inhibition by MK-2206 Represses Colorectal Cancer-Initiating Stem Cells.

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P2860

P2860

Selective AKT Inhibition by MK-2206 Represses Colorectal Cancer-Initiating Stem Cells.

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type

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P1433

P1476

P2093

P2860

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P31

P356

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P478

P50

P577

P5875

P6179

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P921

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P356

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P1476

P2093

P2860

P2888

P304

P31

P356

P433

P478

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P5875

P6179

P698

P921

P932