The Phospholipase Cγ2 Mutants R665W and L845F Identified in Ibrutinib-resistant Chronic Lymphocytic Leukemia Patients Are Hypersensitive to the Rho GTPase Rac2 Protein.
about
Learning from the failures of drug discovery in B-cell non-Hodgkin lymphomas and perspectives for the future: chronic lymphocytic leukemia and diffuse large B-cell lymphoma as two ends of a spectrum in drug development.Pharmacotherapy of relapsed/refractory chronic lymphocytic leukemia.Profile of venetoclax and its potential in the context of treatment of relapsed or refractory chronic lymphocytic leukemia.Clonal evolution leading to ibrutinib resistance in chronic lymphocytic leukemia.Are BTK and PLCG2 mutations necessary and sufficient for ibrutinib resistance in chronic lymphocytic leukemia?Dynamic Allostery in PLCγ1 and Its Modulation by a Cancer Mutation Revealed by MD Simulation and NMRFunctional characterization of phospholipase C-γ mutant protein causing both somatic ibrutinib resistance and a germline monogenic autoinflammatory disorder
P2860
Q38685006-45453235-9E09-4F84-A387-CAEF79F69776Q38818283-8A46EF01-67D9-47C1-A9D7-86D9213DE772Q39145934-029E1586-0DD7-4AA6-9B27-85FDBB9D1E9FQ40397638-D25EE2A7-4AB5-4A54-80A4-3C719F1EE2B3Q49582344-16278991-38C2-43D8-B7D5-0B972868946AQ57752495-EF5C2D1A-84B5-4697-907D-35E71017BDE7Q57821054-9F9B2895-6F03-4E20-915C-F8DF441BB808
P2860
The Phospholipase Cγ2 Mutants R665W and L845F Identified in Ibrutinib-resistant Chronic Lymphocytic Leukemia Patients Are Hypersensitive to the Rho GTPase Rac2 Protein.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
The Phospholipase Cγ2 Mutants ...... o the Rho GTPase Rac2 Protein.
@en
The Phospholipase Cγ2 Mutants ...... o the Rho GTPase Rac2 Protein.
@nl
type
label
The Phospholipase Cγ2 Mutants ...... o the Rho GTPase Rac2 Protein.
@en
The Phospholipase Cγ2 Mutants ...... o the Rho GTPase Rac2 Protein.
@nl
prefLabel
The Phospholipase Cγ2 Mutants ...... o the Rho GTPase Rac2 Protein.
@en
The Phospholipase Cγ2 Mutants ...... o the Rho GTPase Rac2 Protein.
@nl
P2093
P2860
P356
P1476
The Phospholipase Cγ2 Mutants ...... o the Rho GTPase Rac2 Protein.
@en
P2093
Anja Schade
Claudia Walliser
Daniel Mertens
Elisabeth Hermkes
Julia Deinzer
Laurent Désiré
Marc Zapatka
Peter Gierschik
Sebastian Wiese
P2860
P304
22136-22148
P356
10.1074/JBC.M116.746842
P407
P577
2016-08-19T00:00:00Z