about
The Interplay between Circadian System, Cholesterol Synthesis, and Steroidogenesis Affects Various Aspects of Female ReproductionNovel insights into the downstream pathways and targets controlled by transcription factors CREM in the testisDehydroepiandrosterone induces human CYP2B6 through the constitutive androstane receptorAcrolein consumption induces systemic dyslipidemia and lipoprotein modificationPolymorphisms of CYP51A1 from cholesterol synthesis: associations with birth weight and maternal lipid levels and impact on CYP51 protein structure.CYP53A15 of Cochliobolus lunatus, a target for natural antifungal compounds.Combinations of genetic changes in the human cAMP-responsive element modulator gene: a clue towards understanding some forms of male infertility?Effect of CAR activation on selected metabolic pathways in normal and hyperlipidemic mouse livers.Obesity resistant mechanisms in the Lean polygenic mouse model as indicated by liver transcriptome and expression of selected genes in skeletal muscle.New steroid 5alpha-reductase type I (SRD5A1) homologous sequences on human chromosomes 6 and 8.Sterols in spermatogenesis and sperm maturation.Cumulus cells gene expression profiling in terms of oocyte maturity in controlled ovarian hyperstimulation using GnRH agonist or GnRH antagonist.Mouse knockout of the cholesterogenic cytochrome P450 lanosterol 14alpha-demethylase (Cyp51) resembles Antley-Bixler syndromeThe interplay of cis-regulatory elements rules circadian rhythms in mouse liver.The Sterolgene v0 cDNA microarray: a systemic approach to studies of cholesterol homeostasis and drug metabolism.Molecular Interactions between NAFLD and Xenobiotic Metabolism.Mammalian cytochromes P450--importance of tissue specificity.The ubiquitously expressed human CYP51 encodes lanosterol 14 alpha-demethylase, a cytochrome P450 whose expression is regulated by oxysterols.Functional genomics approaches to studies of the cytochrome p450 superfamily.Investigation of the CYP2C9 induction profile in human hepatocytes by combining experimental and modelling approaches.Timing of circadian genes in mammalian tissues.Defects in cholesterol synthesis genes in mouse and in humans: lessons for drug development and safer treatments.Regulation of hepatic cytochromes p450 by lipids and cholesterol.Genomic aspects of NAFLD pathogenesis.Circadian events in human diseases and in cytochrome P450-related drug metabolism and therapy.Steroidal triterpenes of cholesterol synthesis.Amyloid precursor protein α- and β-cleaved ectodomains exert opposing control of cholesterol homeostasis via SREBP2.Large-scale computational models of liver metabolism: How far from the clinics?Novel cholesterol biosynthesis inhibitors targeting human lanosterol 14alpha-demethylase (CYP51).A cAMP-responsive element binding site is essential for sterol regulation of the human lanosterol 14alpha-demethylase gene (CYP51).Acrolein-induced dyslipidemia and acute-phase response are independent of HMG-CoA reductase.Dehydroepiandrosterone post-transcriptionally modifies CYP1A2 induction involving androgen receptor.Nonalcoholic Fatty liver disease: focus on lipoprotein and lipid deregulation.Adaptation of cholesterol synthesis to fasting and TNF-alpha: profiling cholesterol intermediates in the liver, brain, and testis.Initiation of steroidogenesis precedes expression of cholesterologenic enzymes in the fetal mouse testes.Transcriptional activation of PPARalpha by phenobarbital in the absence of CAR and PXR.CREM modulates the circadian expression of CYP51, HMGCR and cholesterogenesis in the liver.Lanosterol 14alpha-demethylase and MAS sterols in mammalian gametogenesis.The human primary hepatocyte transcriptome reveals novel insights into atorvastatin and rosuvastatin action.Low nucleotide variability of CYP51A1 in humans: meta-analysis of cholesterol and bile acid synthesis and xenobiotic metabolism pathways.
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description
hulumtuese
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researcher
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ricercatrice
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wetenschapper
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հետազոտող
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name
Damjana Rozman
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Damjana Rozman
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Damjana Rozman
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Damjana Rozman
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Damjana Rozman
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type
label
Damjana Rozman
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Damjana Rozman
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Damjana Rozman
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Damjana Rozman
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Damjana Rozman
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D Rozman
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prefLabel
Damjana Rozman
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Damjana Rozman
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Damjana Rozman
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Damjana Rozman
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Damjana Rozman
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P106
P21
P214
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P496
0000-0002-6501-2163
P7859
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