APPL1 regulates basal NF-κB activity by stabilizing NIK.

APPL1 regulates basal NF-κB activity by stabilizing NIK.

Item
http://www.wikidata.org/entity/Q42399744
APPL endosomes are not obligatory endocytic intermediates but act as stable cargo-sorting compartments.Absence of Appl2 sensitizes endotoxin shock through activation of PI3K/Akt pathway.Protein-Binding Function of RNA-Dependent Protein Kinase Promotes Proliferation through TRAF2/RIP1/NF-κB/c-Myc Pathway in Pancreatic β cellsEvidence that the rab5 effector APPL1 mediates APP-βCTF-induced dysfunction of endosomes in Down syndrome and Alzheimer's disease.Multifunctional protein APPL2 contributes to survival of human glioma cells.APPL proteins promote TGFβ-induced nuclear transport of the TGFβ type I receptor intracellular domain.Expression of APPL1 is correlated with clinicopathologic characteristics and poor prognosis in patients with gastric cancer.APPL proteins modulate DNA repair and radiation survival of pancreatic carcinoma cells by regulating ATM.APPL1 prevents pancreatic beta cell death and inflammation by dampening NFκB activation in a mouse model of type 1 diabetes.Molecular Consequences of Proprotein Convertase 1/3 (PC1/3) Inhibition in Macrophages for Application to Cancer Immunotherapy: A Proteomic Study.Amyloid precursor protein and endosomal-lysosomal dysfunction in Alzheimer's disease: inseparable partners in a multifactorial disease.Distinct Roles for APPL1 and APPL2 in Regulating Toll-like Receptor 4 Signaling in Macrophages.Dysfunction of autophagy and endosomal-lysosomal pathways: Roles in pathogenesis of Down syndrome and Alzheimer's Disease.Delivery of an miR155 inhibitor by anti-CD20 single-chain antibody into B cells reduces the acetylcholine receptor-specific autoantibodies and ameliorates experimental autoimmune myasthenia gravis.Cell-free formation and interactome analysis of caveolae.
P2860

APPL1 regulates basal NF-κB activity by stabilizing NIK.

Item
http://www.wikidata.org/entity/Q42399744
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
APPL1 regulates basal NF-κB activity by stabilizing NIK.
@en
APPL1 regulates basal NF-κB activity by stabilizing NIK.
@nl
type
label
APPL1 regulates basal NF-κB activity by stabilizing NIK.
@en
APPL1 regulates basal NF-κB activity by stabilizing NIK.
@nl
prefLabel
APPL1 regulates basal NF-κB activity by stabilizing NIK.
@en
APPL1 regulates basal NF-κB activity by stabilizing NIK.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P932
P356
P1433
P1476
APPL1 regulates basal NF-κB activity by stabilizing NIK
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P932