Involvement of MAPK signaling molecules and Runx2 in the NELL1-induced osteoblastic differentiation
about
NELL-1 binds to APR3 affecting human osteoblast proliferation and differentiationSignatures of selection in the genomes of commercial and non-commercial chicken breedsNELL-1 induces Sca-1+ mesenchymal progenitor cell expansion in models of bone maintenance and repair.Nell-1 protein promotes bone formation in a sheep spinal fusion model.Nell-1, a key functional mediator of Runx2, partially rescues calvarial defects in Runx2(+/-) mice.Calvarial cleidocraniodysplasia-like defects with ENU-induced Nell-1 deficiency.Nfatc2 is a primary response gene of Nell-1 regulating chondrogenesis in ATDC5 cells.Identification and characterization of Runx2 phosphorylation sites involved in matrix metalloproteinase-13 promoter activationNovel Wnt Regulator NEL-Like Molecule-1 Antagonizes Adipogenesis and Augments Osteogenesis Induced by Bone Morphogenetic Protein 2NELL-1 injection maintains long-bone quantity and quality in an ovariectomy-induced osteoporotic senile rat model.Vertebral Implantation of NELL-1 Enhances Bone Formation in an Osteoporotic Sheep ModelOpposing TNF-α/IL-1β- and BMP-2-activated MAPK signaling pathways converge on Runx2 to regulate BMP-2-induced osteoblastic differentiation.The role of NELL-1, a growth factor associated with craniosynostosis, in promoting bone regeneration.Oligomerization-induced conformational change in the C-terminal region of Nel-like molecule 1 (NELL1) protein is necessary for the efficient mediation of murine MC3T3-E1 cell adhesion and spreading.Mapping the heparin-binding site of the osteoinductive protein NELL1 by site-directed mutagenesis.Biologic adjuvants and bone: current use in orthopedic surgery.The C-terminal region of NELL1 mediates osteoblastic cell adhesion through integrin α3β1.The over-expression of cell migratory genes in alveolar rhabdomyosarcoma could contribute to metastatic spread.Structure-function analysis of Nel, a thrombospondin-1-like glycoprotein involved in neural development and functions.BMP2-induced inflammation can be suppressed by the osteoinductive growth factor NELL-1.Enhanced osteogenesis by collagen-binding peptide from bone sialoprotein in vitro and in vivo.NELL-1 promotes cell adhesion and differentiation via Integrinβ1.Neural EGFL-Like 1 Is a Downstream Regulator of Runt-Related Transcription Factor 2 in Chondrogenic Differentiation and Maturation.Neural EGFL-Like 1 Regulates Cartilage Maturation through Runt-Related Transcription Factor 3-Mediated Indian Hedgehog Signaling.Neural EGF-like protein 1 (NELL-1): Signaling crosstalk in mesenchymal stem cells and applications in regenerative medicine.Characterization of Runx2 phosphorylation sites required for TGF-β1-mediated stimulation of matrix metalloproteinase-13 expression in osteoblastic cells.
P2860
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P2860
Involvement of MAPK signaling molecules and Runx2 in the NELL1-induced osteoblastic differentiation
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Involvement of MAPK signaling ...... d osteoblastic differentiation
@en
Involvement of MAPK signaling ...... d osteoblastic differentiation
@nl
type
label
Involvement of MAPK signaling ...... d osteoblastic differentiation
@en
Involvement of MAPK signaling ...... d osteoblastic differentiation
@nl
prefLabel
Involvement of MAPK signaling ...... d osteoblastic differentiation
@en
Involvement of MAPK signaling ...... d osteoblastic differentiation
@nl
P2093
P2860
P1433
P1476
Involvement of MAPK signaling ...... d osteoblastic differentiation
@en
P2093
Junichiro Kaku
Katsuyuki Tanizawa
Kenji Tatematsu
Koichi Igarashi
Mitsuo Oda
Nobuyuki Bokui
Shun'ichi Kuroda
Takashi Matsuzaki
Takayuki Otani
P2860
P304
P356
10.1016/J.FEBSLET.2007.12.006
P407
P577
2007-12-17T00:00:00Z