Aerobic glycolysis suppresses p53 activity to provide selective protection from apoptosis upon loss of growth signals or inhibition of BCR-Abl.
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Exploiting mitochondrial dysfunction for effective elimination of imatinib-resistant leukemic cells.mRNA expression in papillary and anaplastic thyroid carcinoma: molecular anatomy of a killing switchAkt requires glucose metabolism to suppress puma expression and prevent apoptosis of leukemic T cells.Degradation of HK2 by chaperone-mediated autophagy promotes metabolic catastrophe and cell deathMetabolic stress in autophagy and cell death pathwaysGlycolysis inhibitor screening identifies the bis-geranylacylphloroglucinol protonophore moronone from Moronobea coccinea.The role of mitochondrial DNA damage and repair in the resistance of BCR/ABL-expressing cells to tyrosine kinase inhibitorsActivated lymphocytes as a metabolic model for carcinogenesis.Suppression of Glut1 and Glucose Metabolism by Decreased Akt/mTORC1 Signaling Drives T Cell Impairment in B Cell Leukemia.Oleanolic Acid Inhibits High Salt-Induced Exaggeration of Warburg-like Metabolism in Breast Cancer Cells.Glucose transporter 1-mediated glucose uptake is limiting for B-cell acute lymphoblastic leukemia anabolic metabolism and resistance to apoptosis.An R132H mutation in isocitrate dehydrogenase 1 enhances p21 expression and inhibits phosphorylation of retinoblastoma protein in glioma cellsS6K1 determines the metabolic requirements for BCR-ABL survival.Akt-dependent glucose metabolism promotes Mcl-1 synthesis to maintain cell survival and resistance to Bcl-2 inhibition.Autophagy is essential to suppress cell stress and to allow BCR-Abl-mediated leukemogenesis.Quantitative- and phospho-proteomic analysis of the yeast response to the tyrosine kinase inhibitor imatinib to pharmacoproteomics-guided drug line extension.The synergism of MCL1 and glycolysis on pediatric acute lymphoblastic leukemia cell survival and prednisolone resistance.Hyperglycemia of tumor microenvironment modulates stage-dependent tumor progression and multidrug resistance: implication of cell survival regulatory molecules and altered glucose transport.Monocarboxylate transporter-1 promotes osteoblast differentiation via suppression of p53, a negative regulator of osteoblast differentiation.
P2860
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P2860
Aerobic glycolysis suppresses p53 activity to provide selective protection from apoptosis upon loss of growth signals or inhibition of BCR-Abl.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Aerobic glycolysis suppresses ...... nals or inhibition of BCR-Abl.
@en
Aerobic glycolysis suppresses ...... nals or inhibition of BCR-Abl.
@nl
type
label
Aerobic glycolysis suppresses ...... nals or inhibition of BCR-Abl.
@en
Aerobic glycolysis suppresses ...... nals or inhibition of BCR-Abl.
@nl
prefLabel
Aerobic glycolysis suppresses ...... nals or inhibition of BCR-Abl.
@en
Aerobic glycolysis suppresses ...... nals or inhibition of BCR-Abl.
@nl
P2093
P2860
P1433
P1476
Aerobic glycolysis suppresses ...... nals or inhibition of BCR-Abl.
@en
P2093
Emily F Mason
Hugh Gannon
Jeffrey C Rathmell
Jonathan L Coloff
Pankuri Goraksha-Hicks
Stephen N Jones
Yuxing Zhao
P2860
P304
P356
10.1158/0008-5472.CAN-10-0608
P407
P577
2010-09-28T00:00:00Z