Discovery and characterization of a novel series of N-phenylsulfonyl-1H-pyrrole picolinamides as positive allosteric modulators of the metabotropic glutamate receptor 4 (mGlu4).

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N-Pyrrylarylsulfones with High Therapeutic Potential.

P2860

Q39173240-39A9D28B-9157-4A22-ABCD-30C1412CDA27

P2860

Discovery and characterization of a novel series of N-phenylsulfonyl-1H-pyrrole picolinamides as positive allosteric modulators of the metabotropic glutamate receptor 4 (mGlu4).

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2016 nî lūn-bûn

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年论文

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2016年论文

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2016年论文

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name

Discovery and characterization ...... glutamate receptor 4 (mGlu4).

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Discovery and characterization ...... abotropic glutamate receptor 4

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Discovery and characterization ...... glutamate receptor 4 (mGlu4).

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Discovery and characterization ...... abotropic glutamate receptor 4

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Discovery and characterization ...... glutamate receptor 4 (mGlu4).

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Discovery and characterization ...... abotropic glutamate receptor 4

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P1476

Discovery and characterization ...... glutamate receptor 4 (mGlu4).

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P2093

Alice L Rodriguez

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Anna L Blobaum

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Corey R Hopkins

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J Scott Daniels

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James M Salovich

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Matthew T Loch

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Rocco D Gogliotti

http://www.w3.org/2001/XMLSchema#string

Ryan M Morrison

http://www.w3.org/2001/XMLSchema#string

Yiu-Yin Cheung

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P2860

Synthesis and evaluation of a series of heterobiarylamides that are centrally penetrant metabotropic glutamate receptor 4 (mGluR4) positive allosteric modulators (PAMs)

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Discovery, synthesis, and structure-activity relationship development of a series of N-(4-acetamido)phenylpicolinamides as positive allosteric modulators of metabotropic glutamate receptor 4 (mGlu(4)) with CNS exposure in rats.

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2984-2987

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scholarly article

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10.1016/J.BMCL.2016.05.029

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English

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Colleen M. Niswender

Craig W. Lindsley

P Jeffrey Conn

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2016-05-11T00:00:00Z

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27234146

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4955388

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Discovery and characterization of a novel series of N-phenylsulfonyl-1H-pyrrole picolinamides as positive allosteric modulators of the metabotropic glutamate receptor 4 (mGlu4).

about

P2860

P2860

Discovery and characterization of a novel series of N-phenylsulfonyl-1H-pyrrole picolinamides as positive allosteric modulators of the metabotropic glutamate receptor 4 (mGlu4).

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