Small molecules that modulate quorum sensing and control virulence in Pseudomonas aeruginosa
about
Bacterial quorum sensing: its role in virulence and possibilities for its controlA family of indoles regulate virulence and Shiga toxin production in pathogenic E. coliSpecificity and complexity in bacterial quorum-sensing systemsStereochemical insignificance discovered in Acinetobacter baumannii quorum sensingPotent and selective synthetic modulators of a quorum sensing repressor in Pseudomonas aeruginosa identified from second-generation libraries of N-acylated L-homoserine lactones.Thiolactone modulators of quorum sensing revealed through library design and screening.Design, synthesis, and biological evaluation of abiotic, non-lactone modulators of LuxR-type quorum sensing.Mutational analysis of the quorum-sensing receptor LasR reveals interactions that govern activation and inhibition by nonlactone ligands.Synthesis and biological evaluation of triazole-containing N-acyl homoserine lactones as quorum sensing modulatorsSynthesis of 'clickable' acylhomoserine lactone quorum sensing probes: unanticipated effects on mammalian cell activationThe hierarchy quorum sensing network in Pseudomonas aeruginosa.Unraveling the contributions of hydrogen-bonding interactions to the activity of native and non-native ligands in the quorum-sensing receptor LasR.Potent and Selective Modulation of the RhlR Quorum Sensing Receptor by Using Non-native Ligands: An Emerging Target for Virulence Control in Pseudomonas aeruginosaInterkingdom Responses to Bacterial Quorum Sensing Signals Regulate Frequency and Rate of Nodulation in Legume-Rhizobia Symbiosis.A Comparative Analysis of Synthetic Quorum Sensing Modulators in Pseudomonas aeruginosa: New Insights into Mechanism, Active Efflux Susceptibility, Phenotypic Response, and Next-Generation Ligand DesignStructure-Based Design and Biological Evaluation of Triphenyl Scaffold-Based Hybrid Compounds as Hydrolytically Stable Modulators of a LuxR-Type Quorum Sensing Receptor.Immunomodulation and the quorum sensing molecule 3-oxo-C12-homoserine lactone: the importance of chemical scaffolding for probe development.Active efflux influences the potency of quorum sensing inhibitors in Pseudomonas aeruginosa.Modulating immunity as a therapy for bacterial infections.Evolution of resistance to quorum-sensing inhibitors.Substituted lactam and cyclic azahemiacetals modulate Pseudomonas aeruginosa quorum sensing.Inhibition of LuxS by S-ribosylhomocysteine analogues containing a [4-aza]ribose ring.Chemical probes of quorum sensing: from compound development to biological discoveryLeaf Extracts of Selected Gardening Trees Can Attenuate Quorum Sensing and Pathogenicity of Pseudomonas aeruginosa PAO1.Bacterial Biofilm Control by Perturbation of Bacterial Signaling Processes.Potent Irreversible Inhibitors of LasR Quorum Sensing in Pseudomonas aeruginosa.Impact of phenolic compounds in the acyl homoserine lactone-mediated quorum sensing regulatory pathways.Chemical methods to interrogate bacterial quorum sensing pathways.S-Ribosylhomocysteine Analogues Modified at the Ribosyl C-4 Position.Synthesis and application of an N-acylated l-homoserine lactone derivatized affinity matrix for the isolation of quorum sensing signal receptors.Acyl-ACP substrate recognition in Burkholderia mallei BmaI1 acyl-homoserine lactone synthase.Molecular Insights into the Impact of Oxidative Stress on the Quorum-Sensing Regulator Protein LasRA new quorum-sensing inhibitor attenuates virulence and decreases antibiotic resistance in Pseudomonas aeruginosa.Synthesis and molecular modeling provide insight into a Pseudomonas aeruginosa quorum sensing conundrum.S-Ribosylhomocysteine analogs containing a [4-thio]ribose ring.Modified N-acyl-homoserine lactones as chemical probes for the elucidation of plant-microbe interactions.Sodium ascorbate as a quorum sensing inhibitor of Pseudomonas aeruginosa.Virtual screening and biological evaluation of biofilm inhibitors on dual targets in quorum sensing system.Asymmetric synthesis of α,β-diamino acid derivatives with an aziridine-, azetidine- and γ-lactone-skeleton via Mannich-type additions across α-chloro-N-sulfinylimines.Mechanism of agonism and antagonism of the Pseudomonas aeruginosa quorum sensing regulator QscR with non-native ligands.
P2860
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P2860
Small molecules that modulate quorum sensing and control virulence in Pseudomonas aeruginosa
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Small molecules that modulate ...... ence in Pseudomonas aeruginosa
@en
Small molecules that modulate ...... ence in Pseudomonas aeruginosa
@nl
type
label
Small molecules that modulate ...... ence in Pseudomonas aeruginosa
@en
Small molecules that modulate ...... ence in Pseudomonas aeruginosa
@nl
prefLabel
Small molecules that modulate ...... ence in Pseudomonas aeruginosa
@en
Small molecules that modulate ...... ence in Pseudomonas aeruginosa
@nl
P2860
P356
P1476
Small molecules that modulate ...... ence in Pseudomonas aeruginosa
@en
P2093
Helen E Blackwell
Margrith E Mattmann
P2860
P304
P356
10.1021/JO101237E
P407
P577
2010-10-01T00:00:00Z