Therapeutic potential of CERE-110 (AAV2-NGF): targeted, stable, and sustained NGF delivery and trophic activity on rodent basal forebrain cholinergic neurons.
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New pharmacological strategies for treatment of Alzheimer's disease: focus on disease modifying drugsMethods, potentials, and limitations of gene delivery to regenerate central nervous system cellsThe stem cell secretome and its role in brain repair.Viral vectors for neurotrophic factor delivery: a gene therapy approach for neurodegenerative diseases of the CNSAlzheimer's disease: The role for neurosurgery.Long-term delivery of nerve growth factor by encapsulated cell biodelivery in the Göttingen minipig basal forebrain.Over-expression of hNGF in adult human olfactory bulb neural stem cells promotes cell growth and oligodendrocytic differentiation.FGF2 gene transfer restores hippocampal functions in mouse models of Alzheimer's disease and has therapeutic implications for neurocognitive disordersTargeted delivery of nerve growth factor to the cholinergic basal forebrain of Alzheimer's disease patients: application of a second-generation encapsulated cell biodelivery device.Long-term reversal of cholinergic neuronal decline in aged non-human primates by lentiviral NGF gene deliveryImmune-directed gene therapeutic development for Alzheimer's, prion, and Parkinson's diseases.Viral vector-mediated gene transfer for CNS disease.Current therapeutic targets for the treatment of Alzheimer's disease.Pharmacologists and Alzheimer disease therapy: to boldly go where no scientist has gone before.Human neural stem cells genetically modified to express human nerve growth factor (NGF) gene restore cognition in the mouse with ibotenic acid-induced cognitive dysfunction.Increased encapsulated cell biodelivery of nerve growth factor in the brain by transposon-mediated gene transfer.Gene Therapy in the Nervous System: Failures and Successes.Gene transfer provides a practical means for safe, long-term, targeted delivery of biologically active neurotrophic factor proteins for neurodegenerative diseases.Low-Affinity Neurotrophin Receptor p75 Promotes the Transduction of Targeted Lentiviral Vectors to Cholinergic Neurons of Rat Basal Forebrain.Adeno-Associated Viral Vector (Serotype 2)-Nerve Growth Factor for Patients With Alzheimer Disease: A Randomized Clinical Trial.Intravenous Transplantation of Human Umbilical Cord Blood Mononuclear Cells Overexpressing Nerve Growth Factor Improves Spatial Memory in APP/PS1 Transgenic Mice with a Model of Alzheimer’s Disease
P2860
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P2860
Therapeutic potential of CERE-110 (AAV2-NGF): targeted, stable, and sustained NGF delivery and trophic activity on rodent basal forebrain cholinergic neurons.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Therapeutic potential of CERE- ...... forebrain cholinergic neurons.
@en
Therapeutic potential of CERE- ...... forebrain cholinergic neurons.
@nl
type
label
Therapeutic potential of CERE- ...... forebrain cholinergic neurons.
@en
Therapeutic potential of CERE- ...... forebrain cholinergic neurons.
@nl
prefLabel
Therapeutic potential of CERE- ...... forebrain cholinergic neurons.
@en
Therapeutic potential of CERE- ...... forebrain cholinergic neurons.
@nl
P2093
P2860
P1476
Therapeutic potential of CERE- ...... forebrain cholinergic neurons.
@en
P2093
Anthony Ramirez
Arpesh Mehta
Eva K Hofer
Kathie M Bishop
Liangwu Sun
Mark Tuszynski
Raymond T Bartus
P2860
P304
P356
10.1016/J.EXPNEUROL.2008.03.004
P407
P577
2008-03-19T00:00:00Z