Central pro-opiomelanocortin gene delivery results in hypophagia, reduced visceral adiposity, and improved insulin sensitivity in genetically obese Zucker rats.
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Deletion of prolyl carboxypeptidase attenuates the metabolic effects of diet-induced obesityProliferative hypothalamic neurospheres express NPY, AGRP, POMC, CART and Orexin-A and differentiate to functional neurons.Moderate long-term modulation of neuropeptide Y in hypothalamic arcuate nucleus induces energy balance alterations in adult rats.Analysis of knockout mice suggests a role for VGF in the control of fat storage and energy expenditureRecent advances in the pharmacology of neurological gene therapy.Pro-opiomelanocortin gene transfer to the nucleus of the solitary track but not arcuate nucleus ameliorates chronic diet-induced obesityReduced anorexigenic efficacy of leptin, but not of the melanocortin receptor agonist melanotan-II, predicts diet-induced obesity in rats.Behavioral and pharmacologic therapies for obesity.Simultaneous POMC gene transfer to hypothalamus and brainstem increases physical activity, lipolysis and reduces adult-onset obesity.Hypothalamic proopiomelanocortin processing and the regulation of energy balanceActivation of the central melanocortin system contributes to the increased arterial pressure in obese Zucker rats.High-fat feeding promotes obesity via insulin receptor/PI3K-dependent inhibition of SF-1 VMH neurons.The brain-adipose axis: a review of involvement of molecules.Energy balance and hypothalamic effects of a high-protein/low-carbohydrate diet.Germline ablation of VGF increases lipolysis in white adipose tissue.Role of hindbrain melanocortin-4 receptor activity in controlling cardiovascular and metabolic functions in spontaneously hypertensive rats.Alterations in phosphorylated CREB expression in different brain regions following short- and long-term morphine exposure: relationship to food intake.Neuroendocrine and cardiac metabolic dysfunction and NLRP3 inflammasome activation in adipose tissue and pancreas following chronic spinal cord injury in the mouse.Controlling feeding behavior by chemical or gene-directed targeting in the brain: what's so spatial about our methods?Participation of the central melanocortin system in metabolic regulation and energy homeostasis.Intermittent MTII application evokes repeated anorexia and robust fat and weight loss.Effects of variants in proopiomelanocortin and neuropeptide y genes on growth, carcass, and meat quality traits in rabbitsLentivirus-mediated α-melanocyte-stimulating hormone overexpression in the hypothalamus decreases diet induced obesity in mice.Endogenous ACTH, not only alpha-melanocyte-stimulating hormone, reduces food intake mediated by hypothalamic mechanisms.Overexpression of CART in the PVN increases food intake and weight gain in rats.Pituitary adenylate cyclase-activating polypeptide inhibits food intake in mice through activation of the hypothalamic melanocortin system.Reduced expression of the KATP channel subunit, Kir6.2, is associated with decreased expression of neuropeptide Y and agouti-related protein in the hypothalami of Zucker diabetic fatty rats.Molecular Therapy of Melanocortin-4-Receptor Obesity by an Autoregulatory BDNF Vector.Melanocortin activation of nucleus of the solitary tract avoids anorectic tachyphylaxis and induces prolonged weight loss.Transgenic MSH overexpression attenuates the metabolic effects of a high-fat diet.Constant heat stress reduces skeletal muscle protein deposition in broilers.
P2860
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P2860
Central pro-opiomelanocortin gene delivery results in hypophagia, reduced visceral adiposity, and improved insulin sensitivity in genetically obese Zucker rats.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Central pro-opiomelanocortin g ...... genetically obese Zucker rats.
@en
Central pro-opiomelanocortin g ...... genetically obese Zucker rats.
@nl
type
label
Central pro-opiomelanocortin g ...... genetically obese Zucker rats.
@en
Central pro-opiomelanocortin g ...... genetically obese Zucker rats.
@nl
prefLabel
Central pro-opiomelanocortin g ...... genetically obese Zucker rats.
@en
Central pro-opiomelanocortin g ...... genetically obese Zucker rats.
@nl
P1433
P1476
Central pro-opiomelanocortin g ...... genetically obese Zucker rats.
@en
P2093
Philip J Scarpace
P304
P356
10.2337/DIABETES.52.8.1951
P407
P577
2003-08-01T00:00:00Z