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The somatostatin analogue octreotide inhibits growth of small intestine neuroendocrine tumour cellsRegulation of pituitary cell function by adiponectinA novel human ghrelin variant (In1-ghrelin) and ghrelin-O-acyltransferase are overexpressed in breast cancer: potential pathophysiological relevance.Somatostatin and its receptors from fish to mammals.Elevated GH/IGF-I promotes mammary tumors in high-fat, but not low-fat, fed miceRole of endogenous cortistatin in the regulation of ghrelin system expression at pancreatic level under normal and obese conditions.Research progress in the stimulatory inputs regulating growth hormone (GH) secretion.Melatonin regulates somatotrope and lactotrope function through common and distinct signaling pathways in cultured primary pituitary cells from female primatesObesity alters gene expression for GH/IGF-I axis in mouse mammary fat pads: differential role of cortistatin and somatostatin.Truncated somatostatin receptor variant sst5TMD4 confers aggressive features (proliferation, invasion and reduced octreotide response) to somatotropinomasKisspeptin regulates gonadotroph and somatotroph function in nonhuman primate pituitary via common and distinct signaling mechanismsLeptin and fasting regulate rat gastric glucose-regulated protein 58.Role of ghrelin system in neuroprotection and cognitive functions: implications in Alzheimer's disease.Cortistatin is not a somatostatin analogue but stimulates prolactin release and inhibits GH and ACTH in a gender-dependent fashion: potential role of ghrelin.Homologous and heterologous in vitro regulation of pituitary receptors for somatostatin, growth hormone (GH)-releasing hormone, and ghrelin in a nonhuman primate (Papio anubis).Mediterranean diet supplemented with coenzyme Q10 induces postprandial changes in p53 in response to oxidative DNA damage in elderly subjects.Molecular Characterization of Growth Hormone-producing Tumors in the GC Rat Model of AcromegalyIn1-ghrelin splicing variant is overexpressed in pituitary adenomas and increases their aggressive features.Lack of cortistatin or somatostatin differentially influences DMBA-induced mammary gland tumorigenesis in mice in an obesity-dependent mode.Presence of sst5TMD4, a truncated splice variant of the somatostatin receptor subtype 5, is associated to features of increased aggressiveness in pancreatic neuroendocrine tumors.Endogenous somatostatin is critical in regulating the acute effects of L-arginine on growth hormone and insulin release in mice.Insulin and IGF-I inhibit GH synthesis and release in vitro and in vivo by separate mechanisms.Serum Galanin Levels in Young Healthy Lean and Obese Non-Diabetic Men during an Oral Glucose Tolerance Test.Intracellular signaling pathways activated by kisspeptins through GPR54: do multiple signals underlie function diversity?Self-limited acute hepatotoxicity caused by pegvisomant.Obesity- and gender-dependent role of endogenous somatostatin and cortistatin in the regulation of endocrine and metabolic homeostasis in mice.Understanding the multifactorial control of growth hormone release by somatotropes: lessons from comparative endocrinology.Clinical Efficacy of Two Different Methods to Initiate Sensor-Augmented Insulin Pumps: A Randomized Controlled Trial.The truncated isoform of somatostatin receptor5 (sst5TMD4) is associated with poorly differentiated thyroid cancer.BIM-23A760 influences key functional endpoints in pituitary adenomas and normal pituitaries: molecular mechanisms underlying the differential response in adenomas.The truncated somatostatin receptor sst5TMD4 stimulates the angiogenic process and is associated to lymphatic metastasis and disease-free survival in breast cancer patients.Obestatin plays an opposite role in the regulation of pituitary somatotrope and corticotrope function in female primates and male/female mice.Molecular pathogenesis of neuroendocrine tumors: implications for current and future therapeutic approaches.Ghrelin gene products, receptors, and GOAT enzyme: biological and pathophysiological insight.Gastrointestinal neuroendocrine tumors (NETs): new diagnostic and therapeutic challenges.Nutritional, hormonal, and depot-dependent regulation of the expression of the small GTPase Rab18 in rodent adipose tissue.Ghrelin O-acyltransferase (GOAT) enzyme is overexpressed in prostate cancer, and its levels are associated with patient's metabolic status: Potential value as a non-invasive biomarker.The components of somatostatin and ghrelin systems are altered in neuroendocrine lung carcinoids and associated to clinical-histological features.Metformin Reduces Prostate Tumor Growth, in a Diet-Dependent Manner, by Modulating Multiple Signaling Pathways.Adipokines (Leptin, Adiponectin, Resistin) Differentially Regulate All Hormonal Cell Types in Primary Anterior Pituitary Cell Cultures from Two Primate Species
P50
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P50
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Justo P. Castaño
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Justo P. Castaño
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Justo P. Castaño
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Justo P. Castaño
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Justo P. Castaño
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Justo P. Castaño
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Justo P. Castaño
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Justo P. Castaño
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Justo P. Castaño
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Justo P. Castaño
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Justo P. Castaño
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Justo P. Castaño
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Justo P. Castaño
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Justo P. Castaño
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Justo P. Castaño
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P106
P1153
7005931268
P21
P31
P496
0000-0002-3145-7287