Critical role for protein phosphatase 2A heterotrimers in mammalian cell survival.
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The antagonistic action of B56-containing protein phosphatase 2As and casein kinase 2 controls the phosphorylation and Gli turnover function of Daz interacting protein 1PP2A regulates BCL-2 phosphorylation and proteasome-mediated degradation at the endoplasmic reticulumLeucine carboxyl methyltransferase-1 is necessary for normal progression through mitosis in mammalian cellsThe broken "Off" switch in cancer signaling: PP2A as a regulator of tumorigenesis, drug resistance, and immune surveillanceThe biogenesis of active protein phosphatase 2A holoenzymes: a tightly regulated process creating phosphatase specificityStructural basis of protein phosphatase 2A stable latencyStructural basis of PP2A activation by PTPA, an ATP-dependent activation chaperone.Molecular basis for PP2A regulatory subunit B56alpha targeting in cardiomyocytesProtein Phosphatase Methyl-Esterase PME-1 Protects Protein Phosphatase 2A from Ubiquitin/Proteasome DegradationUnfolding-resistant translocase targeting: a novel mechanism for outer mitochondrial membrane localization exemplified by the Bbeta2 regulatory subunit of protein phosphatase 2AMicroarray analysis of oxidative stress regulated genes in mesencephalic dopaminergic neuronal cells: relevance to oxidative damage in Parkinson's diseaseThe protein phosphatase 2A regulatory subunits B'beta and B'delta mediate sustained TrkA neurotrophin receptor autophosphorylation and neuronal differentiationAlpha4 is an essential regulator of PP2A phosphatase activityEndotoxin conditioning induces VCP/p97-mediated and inducible nitric-oxide synthase-dependent Tyr284 nitration in protein phosphatase 2A.PP2A-mediated dephosphorylation of p107 plays a critical role in chondrocyte cell cycle arrest by FGFAn endogenous serine/threonine protein phosphatase inhibitor, G-substrate, reduces vulnerability in models of Parkinson's disease.Oxidative stress promotes autophagic cell death in human neuroblastoma cells with ectopic transfer of mitochondrial PPP2R2B (Bbeta2).Protein Phosphatase 2A (PP2A) Regulates EG5 to Control Mitotic ProgressionTau potentiates nerve growth factor-induced mitogen-activated protein kinase signaling and neurite initiation without a requirement for microtubule binding.Inhibition of protein phosphatase 2A (PP2A) prevents Mcl-1 protein dephosphorylation at the Thr-163/Ser-159 phosphodegron, dramatically reducing expression in Mcl-1-amplified lymphoma cells.The protein phosphatase 2A regulatory subunit B55α is a modulator of signaling and microRNA expression in acute myeloid leukemia cells.Phosphatase: PP2A structural importance, regulation and its aberrant expression in cancer.Loss of Acinus inhibits oligonucleosomal DNA fragmentation but not chromatin condensation during apoptosis.Regulation of nuclear-cytoplasmic shuttling and function of Family with sequence similarity 13, member A (Fam13a), by B56-containing PP2As and Akt.Human cancer-associated mutations in the Aα subunit of protein phosphatase 2A increase lung cancer incidence in Aα knock-in and knockout mice.Low expression of PP2A regulatory subunit B55α is associated with T308 phosphorylation of AKT and shorter complete remission duration in acute myeloid leukemia patients.B56δ-related protein phosphatase 2A dysfunction identified in patients with intellectual disability.Protein phosphatase 2A regulates life and death decisions via Akt in a context-dependent manner.Disruption and inactivation of the PP2A complex promotes the proliferation and angiogenesis of hemangioma endothelial cells through activating AKT and ERK.B'-protein phosphatase 2A is a functional binding partner of delta-retroviral integrase.Selective proteasomal degradation of the B'β subunit of protein phosphatase 2A by the E3 ubiquitin ligase adaptor Kelch-like 15Cdc55p-mediated E4orf4 growth inhibition in Saccharomyces cerevisiae is mediated only in part via the catalytic subunit of protein phosphatase 2A.Modulation of protein phosphatase 2A activity alters androgen-independent growth of prostate cancer cells: therapeutic implicationsProtein phosphatase 2A has an essential role in the activation of gamma-irradiation-induced G2/M checkpoint response.PKR regulates B56(alpha)-mediated BCL2 phosphatase activity in acute lymphoblastic leukemia-derived REH cellsNovel Ser/Thr protein phosphatases in cell death regulationFAM122A, a new endogenous inhibitor of protein phosphatase 2ARole of Protein Phosphatase 2A in Osteoblast Differentiation and Function.Functions of B56-containing PP2As in major developmental and cancer signaling pathways.The Interplay between PP2A and microRNAs in Leukemia.
P2860
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P2860
Critical role for protein phosphatase 2A heterotrimers in mammalian cell survival.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Critical role for protein phosphatase 2A heterotrimers in mammalian cell survival.
@en
Critical role for protein phosphatase 2A heterotrimers in mammalian cell survival.
@nl
type
label
Critical role for protein phosphatase 2A heterotrimers in mammalian cell survival.
@en
Critical role for protein phosphatase 2A heterotrimers in mammalian cell survival.
@nl
prefLabel
Critical role for protein phosphatase 2A heterotrimers in mammalian cell survival.
@en
Critical role for protein phosphatase 2A heterotrimers in mammalian cell survival.
@nl
P356
P1476
Critical role for protein phosphatase 2A heterotrimers in mammalian cell survival
@en
P2093
J Thomas Cribbs
Lisa Gomez
P304
47732-47739
P356
10.1074/JBC.M408015200
P407
P577
2004-09-09T00:00:00Z