Ectodomain shedding of the hypoxia-induced carbonic anhydrase IX is a metalloprotease-dependent process regulated by TACE/ADAM17.
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Sensitization of cerebral tissue in nude mice with photodynamic therapy induces ADAM17/TACE and promotes glioma cell invasion.3'UTR polymorphisms of carbonic anhydrase IX determine the miR-34a targeting efficiency and prognosis of hepatocellular carcinoma.High levels of carbonic anhydrase IX in tumour tissue and plasma are biomarkers of poor prognostic in patients with non-small cell lung cancerTumor microenvironmental changes induced by the sulfamate carbonic anhydrase IX inhibitor S4 in a laryngeal tumor modelMeasuring carbonic anhydrase IX as a hypoxia biomarker: differences in concentrations in serum and plasma using a commercial enzyme-linked immunosorbent assay due to influences of metal ions.Protein shedding in urothelial bladder cancer: prognostic implications of soluble urinary EGFR and EpCAM.Apoptosis-induced ectodomain shedding of hypoxia-regulated carbonic anhydrase IX from tumor cells: a double-edged response to chemotherapy.Carbonic anhydrase IX is a clinically significant tissue and serum biomarker associated with renal cell carcinomaRole of carbonic anhydrases in the progression of renal cell carcinoma subtypes: proposal of a unified hypothesis.Carbonic anhydrase IX from cancer-associated fibroblasts drives epithelial-mesenchymal transition in prostate carcinoma cells.Molecular mechanisms of carbonic anhydrase IX-mediated pH regulation under hypoxia.Carbonic anhydrase IX has chaperone-like functions and is an immunoadjuvant.Role of ADAM17 in invasion and migration of CD133-expressing liver cancer stem cells after irradiation.ADAM17 promotes breast cancer cell malignant phenotype through EGFR-PI3K-AKT activation.Histopathological determinants of tumor resistance: a special look to the immunohistochemical expression of carbonic anhydrase IX in human cancers.Carbonic anhydrase IX as an imaging and therapeutic target for tumors and metastases.Carbonic anhydrase IX, a hypoxia-induced catalytic component of the pH regulating machinery in tumors.Carbonic anhydrase IX: a hypoxia-controlled "catalyst" of cell migration.Carbonic anhydrase IX is a marker of hypoxia and correlates with higher Gleason scores and ISUP grading in prostate cancer.Improved decision making for prioritizing tumor targeting antibodies in human xenografts: Utility of fluorescence imaging to verify tumor target expression, antibody binding and optimization of dosage and application scheduleADAM17 promotes glioma cell malignant phenotypeIntact intracellular tail is critical for proper functioning of the tumor-associated, hypoxia-regulated carbonic anhydrase IX.SCUBE1: a promising biomarker in renal cell cancerTumor antigen glycosaminoglycan modification regulates antibody-drug conjugate delivery and cytotoxicity.Pulmonary delivery of triptolide-loaded liposomes decorated with anti-carbonic anhydrase IX antibody for lung cancer therapy.Recent Advances in ADAM17 Research: A Promising Target for Cancer and Inflammation.Carbonic anhydrase IX inhibition affects viability of cancer cells adapted to extracellular acidosis.Cancer metabolism: New insights into classic characteristics.Novel fluorinated carbonic anhydrase IX inhibitors reduce hypoxia-induced acidification and clonogenic survival of cancer cells.
P2860
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P2860
Ectodomain shedding of the hypoxia-induced carbonic anhydrase IX is a metalloprotease-dependent process regulated by TACE/ADAM17.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Ectodomain shedding of the hyp ...... cess regulated by TACE/ADAM17.
@en
Ectodomain shedding of the hyp ...... cess regulated by TACE/ADAM17.
@nl
type
label
Ectodomain shedding of the hyp ...... cess regulated by TACE/ADAM17.
@en
Ectodomain shedding of the hyp ...... cess regulated by TACE/ADAM17.
@nl
prefLabel
Ectodomain shedding of the hyp ...... cess regulated by TACE/ADAM17.
@en
Ectodomain shedding of the hyp ...... cess regulated by TACE/ADAM17.
@nl
P2093
P2860
P356
P1476
Ectodomain shedding of the hyp ...... ocess regulated by TACE/ADAM17
@en
P2093
E Svastova
J Pastorek
M Zatovicova
O Sedlakova
S Pastorekova
P2860
P2888
P304
P356
10.1038/SJ.BJC.6602861
P407
P577
2005-11-01T00:00:00Z