Constitutively active phosphatidylinositol 3-kinase and AKT are sufficient to stimulate the epithelial Na+/H+ exchanger 3.
about
Glucocorticoids acutely increase cell surface Na+/H+ exchanger-3 (NHE3) by activation of NHE3 exocytosis.Oestrogens and spermatogenesis.Akt2 phosphorylates ezrin to trigger NHE3 translocation and activationNHE3 mobility in brush borders increases upon NHERF2-dependent stimulation by lyophosphatidic acid.Insulin resistance, obesity, hypertension, and renal sodium transport.Akt as a mediator of cell death.Rapamycin Inhibition of mTOR Reduces Levels of the Na+/H+ Exchanger 3 in Intestines of Mice and Humans, Leading to Diarrhea.Emerging roles of alkali cation/proton exchangers in organellar homeostasis.Estrogen-dependent and -independent estrogen receptor-alpha signaling separately regulate male fertilityAlpha2-adrenergic receptors attenuate secretagogue-induced endocytosis and promote exocytosis of intestinal NHE2 and NHE3.Mechanisms of the regulation of the intestinal Na+/H+ exchanger NHE3AKT and GSK-3 are necessary for direct ezrin binding to NHE3 as part of a C-terminal stimulatory complex: role of a novel Ser-rich NHE3 C-terminal motif in NHE3 activity and trafficking.The sodium pump and cardiotonic steroids-induced signal transduction protein kinases and calcium-signaling microdomain in regulation of transporter trafficking.Na+/H+ exchangers.Akt2-Dependent Phosphorylation of Radixin in Regulation of Mrp-2 Trafficking in WIF-B Cells.Impaired intestinal NHE3 activity in the PDK1 hypomorphic mouse.Gs protein-coupled receptor agonists induce transactivation of the epidermal growth factor receptor in T84 cells: implications for epithelial secretory responses.Lysophosphatidic acid stimulates brush border Na+/H+ exchanger 3 (NHE3) activity by increasing its exocytosis by an NHE3 kinase A regulatory protein-dependent mechanism.Phosphorylation of NHE3-S719 regulates NHE3 activity through the formation of multiple signaling complexes.3,3',5-Triiodo-L-thyronine up-regulation of Na,K-ATPase activity and cell surface expression in alveolar epithelial cells is Src kinase- and phosphoinositide 3-kinase-dependent.Sgk-1 is a positive regulator of constitutive albumin uptake in renal proximal tubule cells.
P2860
Q33818285-06CCAE96-FFD5-4F30-A6C2-3368730B1CABQ33856966-6E26A2D7-EA34-47BD-9FF3-5841A9D64887Q34049636-EADD316D-0691-49D9-952F-62A2ABCB3E38Q34116039-BD7B4449-D18D-429D-B18F-10FE7C38F54AQ34985526-C5889708-B533-432F-9A79-FA6735069EE2Q36161549-D31C3E6E-43A4-43FE-A1EF-1A0EFC519CBFQ36848529-D52EEDA8-E661-44C9-BE14-0FA4EA6149A4Q36889613-97D952C9-B712-495E-9562-6B14E16D57A3Q37210764-35EA41CD-5EA3-481B-8B0C-071EBED79527Q37312866-FB4B408E-AEAE-4573-9520-F2690EB6EECCQ37462304-FE14D7DE-7268-40A6-BFED-C035B3532216Q37608417-57E0587A-4551-4709-8676-07B6255298F1Q37689977-2E210704-3E3B-4FD9-BF07-869F19C33CBDQ38111734-788E2C5B-C877-41F3-A3FF-69B9503D7D5EQ38824980-CC74AE46-B288-44BD-8A70-E35681740540Q40258022-B12C7C0A-CC9F-449E-A0F7-DC25215BEBFDQ40609831-74B1402A-27A2-46E8-ADD6-2C9A4AC40C09Q40669337-41EC5A07-C9FE-4048-85F7-F99EFCE41209Q41001492-38DF5CF1-44DA-46A7-89C3-2B3B1A4AF078Q45040995-6F0C843B-6424-4C17-BB52-395A063FFB86Q50501776-81D7CCE8-6B52-442D-829E-B10F5667F35D
P2860
Constitutively active phosphatidylinositol 3-kinase and AKT are sufficient to stimulate the epithelial Na+/H+ exchanger 3.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Constitutively active phosphat ...... epithelial Na+/H+ exchanger 3.
@en
Constitutively active phosphat ...... epithelial Na+/H+ exchanger 3.
@nl
type
label
Constitutively active phosphat ...... epithelial Na+/H+ exchanger 3.
@en
Constitutively active phosphat ...... epithelial Na+/H+ exchanger 3.
@nl
prefLabel
Constitutively active phosphat ...... epithelial Na+/H+ exchanger 3.
@en
Constitutively active phosphat ...... epithelial Na+/H+ exchanger 3.
@nl
P2093
P2860
P356
P1476
Constitutively active phosphat ...... epithelial Na+/H+ exchanger 3.
@en
P2093
Donowitz M
Lee-Kwon W
Tsichlis P
P2860
P304
31296-31304
P356
10.1074/JBC.M103900200
P407
P577
2001-05-25T00:00:00Z