The social defeat animal model of depression shows diminished levels of orexin in mesocortical regions of the dopamine system, and of dynorphin and orexin in the hypothalamus.
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The Addictive Model of Self-Harming (Non-suicidal and Suicidal) BehaviorUnderstanding how discrete populations of hypothalamic neurons orchestrate complicated behavioral statesOrexin antagonists for neuropsychiatric disease: progress and potential pitfallsSocial stress models in depression research: what do they tell us?Captodiamine, a putative antidepressant, enhances hypothalamic BDNF expression in vivo by synergistic 5-HT2c receptor antagonism and sigma-1 receptor agonismSocial agonistic distress in male and female mice: changes of behavior and brain monoamine functioning in relation to acute and chronic challenges.Feasibility and safety of continuous and chronic bilateral deep brain stimulation of the medial forebrain bundle in the naïve Sprague-Dawley rat.Attenuated orexinergic signaling underlies depression-like responses induced by daytime light deficiency.Exercise reverses the effects of early life stress on orexin cell reactivity in male but not female rats.Optogenetic stimulation of accumbens shell or shell projections to lateral hypothalamus produce differential effects on the motivation for cocaineThe kappa opioid receptor: from addiction to depression, and back.Witnessing traumatic events causes severe behavioral impairments in rats.Binge-like consumption of ethanol and other salient reinforcers is blocked by orexin-1 receptor inhibition and leads to a reduction of hypothalamic orexin immunoreactivity.CDH13 and HCRTR2 May Be Associated with Hypersomnia Symptom of Bipolar Depression: A Genome-Wide Functional Enrichment Pathway AnalysisEscalation of cocaine self-administration in adulthood after social defeat of adolescent rats: role of social experience and adaptive coping behaviorEarly life social stress induced changes in depression and anxiety associated neural pathways which are correlated with impaired maternal care.Serotonin-2C and -2a receptor co-expression on cells in the rat medial prefrontal cortex.CRF type 1 receptor antagonism in ventral tegmental area of adolescent rats during social defeat: prevention of escalated cocaine self-administration in adulthood and behavioral adaptations during adolescenceHypocretin (orexin) facilitates reward by attenuating the antireward effects of its cotransmitter dynorphin in ventral tegmental area.Role of orexin in the pathophysiology of depression: potential for pharmacological intervention.Orexin/hypocretin based pharmacotherapies for the treatment of addiction: DORA or SORA?Social defeat protocol and relevant biomarkers, implications for stress response physiology, drug abuse, mood disorders and individual stress vulnerability: a systematic review of the last decade.Hypocretins, Neural Systems, Physiology, and Psychiatric Disorders.New directions for the treatment of depression: Targeting the photic regulation of arousal and mood (PRAM) pathway.Orexin Receptor Multimerization versus Functional Interactions: Neuropharmacological Implications for Opioid and Cannabinoid Signalling and Pharmacogenetics.The Psycho-Neurology of Cross-Species Affective/Social Neuroscience: Understanding Animal Affective States as a Guide to Development of Novel Psychiatric Treatments.Role of the Orexin/Hypocretin System in Stress-Related Psychiatric Disorders.Brain-region-specific Molecular Responses to Maternal Separation and Social Defeat Stress in Mice.Chronic light exposure alters serotonergic and orexinergic systems in the rat brain and reverses maternal separation-induced increase in orexin receptors in the prefrontal cortex.The hypocretin/orexin system as a target for excessive motivation in alcohol use disorders.Social defeat stress and escalation of cocaine and alcohol consumption: Focus on CRF
P2860
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P2860
The social defeat animal model of depression shows diminished levels of orexin in mesocortical regions of the dopamine system, and of dynorphin and orexin in the hypothalamus.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
@zh-hant
name
The social defeat animal model ...... nd orexin in the hypothalamus.
@en
The social defeat animal model ...... nd orexin in the hypothalamus.
@nl
type
label
The social defeat animal model ...... nd orexin in the hypothalamus.
@en
The social defeat animal model ...... nd orexin in the hypothalamus.
@nl
prefLabel
The social defeat animal model ...... nd orexin in the hypothalamus.
@en
The social defeat animal model ...... nd orexin in the hypothalamus.
@nl
P2093
P1433
P1476
The social defeat animal model ...... nd orexin in the hypothalamus.
@en
P2093
P304
P356
10.1016/J.NEUROSCIENCE.2012.05.033
P407
P577
2012-05-22T00:00:00Z