Hedgehog is involved in prostate basal cell hyperplasia formation and its progressing towards tumorigenesis.
about
Molecular biomarkers of cancer stem/progenitor cells associated with progression, metastases, and treatment resistance of aggressive cancersCytotoxic effects induced by docetaxel, gefitinib, and cyclopamine on side population and nonside population cell fractions from human invasive prostate cancer cells.GLI1 confers profound phenotypic changes upon LNCaP prostate cancer cells that include the acquisition of a hormone independent stateNew promising drug targets in cancer- and metastasis-initiating cells.Frequent deregulations in the hedgehog signaling network and cross-talks with the epidermal growth factor receptor pathway involved in cancer progression and targeted therapies.Novel therapies against aggressive and recurrent epithelial cancers by molecular targeting tumor- and metastasis-initiating cells and their progenies.Hedgehog overexpression leads to the formation of prostate cancer stem cells with metastatic property irrespective of androgen receptor expression in the mouse modelDietary zerumbone prevents mouse cornea from UVB-induced photokeratitis through inhibition of NF-κB, iNOS, and TNF-α expression and reduction of MDA accumulation.Intravitreal homocysteine-thiolactone injection leads to the degeneration of multiple retinal cells, including photoreceptors.Frequent gene products and molecular pathways altered in prostate cancer- and metastasis-initiating cells and their progenies and novel promising multitargeted therapies.Animal models relevant to human prostate carcinogenesis underlining the critical implication of prostatic stem/progenitor cells.Low concentrations of 5-aza-2'-deoxycytidine induce breast cancer stem cell differentiation by triggering tumor suppressor gene expression.Functions of normal and malignant prostatic stem/progenitor cells in tissue regeneration and cancer progression and novel targeting therapies.Targeting of cancer stem/progenitor cells plus stem cell-based therapies: the ultimate hope for treating and curing aggressive and recurrent cancers.The GLI1 splice variant TGLI1 promotes glioblastoma angiogenesis and growth.Congenital eye malformations associated with extensive periocular neural crest apoptosis after influenza B virus infection during early embryogenesis.Altered gene products involved in the malignant reprogramming of cancer stem/progenitor cells and multitargeted therapies.Improvement of cytotoxic effects induced by mitoxantrone on hormone-refractory metastatic prostate cancer cells by co-targeting epidermal growth factor receptor and hedgehog signaling cascades.Prostate stem cells in the development of benign prostate hyperplasia and prostate cancer: emerging role and concepts.Correlation of hepatitis C and prostate cancer, inverse correlation of basal cell hyperplasia or prostatitis and epidemic syphilis of unknown duration.KCTD11 tumor suppressor gene expression is reduced in prostate adenocarcinoma.
P2860
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P2860
Hedgehog is involved in prostate basal cell hyperplasia formation and its progressing towards tumorigenesis.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Hedgehog is involved in prosta ...... ressing towards tumorigenesis.
@en
Hedgehog is involved in prosta ...... ressing towards tumorigenesis.
@nl
type
label
Hedgehog is involved in prosta ...... ressing towards tumorigenesis.
@en
Hedgehog is involved in prosta ...... ressing towards tumorigenesis.
@nl
prefLabel
Hedgehog is involved in prosta ...... ressing towards tumorigenesis.
@en
Hedgehog is involved in prosta ...... ressing towards tumorigenesis.
@nl
P2093
P1476
Hedgehog is involved in prosta ...... ressing towards tumorigenesis.
@en
P2093
Bo-Yie Chen
Chi-Rei Yang
Chin-Pao Chang
David P C Lin
Han-Hsin Chang
Jer-Yuh Liu
Wei-Yuh Lo
Wu-Hsien Kuo
P304
P356
10.1016/J.BBRC.2007.04.091
P407
P577
2007-04-20T00:00:00Z