Cytoplasmic Hsp70 promotes ubiquitination for endoplasmic reticulum-associated degradation of a misfolded mutant of the yeast plasma membrane ATPase, PMA1.
about
DNAJs: more than substrate delivery to HSPAQuality control and fate determination of Hsp90 client proteinsDissecting the ER-associated degradation of a misfolded polytopic membrane protein.Previously unknown role for the ubiquitin ligase Ubr1 in endoplasmic reticulum-associated protein degradation.Ubr1 and Ubr2 function in a quality control pathway for degradation of unfolded cytosolic proteins.A mutant plasma membrane protein is stabilized upon loss of Yvh1, a novel ribosome assembly factor.The requirements of yeast Hsp70 of SSA family for the ubiquitin-dependent degradation of short-lived and abnormal proteins.Degradation of a cytosolic protein requires endoplasmic reticulum-associated degradation machinery.The endoplasmic reticulum-associated Hsp40 DNAJB12 and Hsc70 cooperate to facilitate RMA1 E3-dependent degradation of nascent CFTRDeltaF508Ubiquitin conjugation triggers misfolded protein sequestration into quality control foci when Hsp70 chaperone levels are limiting.Usa1 protein facilitates substrate ubiquitylation through two separate domainsThe BiP molecular chaperone plays multiple roles during the biogenesis of torsinA, an AAA+ ATPase associated with the neurological disease early-onset torsion dystonia.The endoplasmic reticulum-associated degradation of the epithelial sodium channel requires a unique complement of molecular chaperones.Hsp110 chaperones control client fate determination in the hsp70-Hsp90 chaperone systemEstablishment of an in vitro transport assay that reveals mechanistic differences in cytosolic events controlling cholera toxin and T-cell receptor α retro-translocationPerformance of protein disorder prediction programs on amino acid substitutions.Hsp70 clears misfolded kinases that partitioned into distinct quality-control compartments.Polypeptide transfer from Hsp40 to Hsp70 molecular chaperones.The thiazide-sensitive NaCl cotransporter is targeted for chaperone-dependent endoplasmic reticulum-associated degradation.Mutations in the Yeast Hsp70, Ssa1, at P417 Alter ATP Cycling, Interdomain Coupling, and Specific Chaperone Functions.Heat shock response relieves ER stress.The Lhs1/GRP170 chaperones facilitate the endoplasmic reticulum-associated degradation of the epithelial sodium channelMicroarray based analysis of temperature and oxidative stress induced messenger RNA in Schistosoma mansoni.A Conserved C-terminal Element in the Yeast Doa10 and Human MARCH6 Ubiquitin Ligases Required for Selective Substrate Degradation.ESCRT regulates surface expression of the Kir2.1 potassium channel.Hul5 ubiquitin ligase: good riddance to bad proteinsThe secretory pathway: exploring yeast diversity.Endoplasmic reticulum stress-induced degradation of DNAJB12 stimulates BOK accumulation and primes cancer cells for apoptosis.The evolving role of ubiquitin modification in endoplasmic reticulum-associated degradation.Exposure of bipartite hydrophobic signal triggers nuclear quality control of Ndc10 at the endoplasmic reticulum/nuclear envelope.An atypical unfolded protein response in heat shocked cells.Proteolytic degradation of regulator of G protein signaling 2 facilitates temporal regulation of Gq/11 signaling and vascular contraction.A Futile Battle? Protein Quality Control and the Stress of Aging.The degradation pathway of a model misfolded protein is determined by aggregation propensity.
P2860
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P2860
Cytoplasmic Hsp70 promotes ubiquitination for endoplasmic reticulum-associated degradation of a misfolded mutant of the yeast plasma membrane ATPase, PMA1.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
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2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
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2007年學術文章
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2007年學術文章
@zh-hant
name
Cytoplasmic Hsp70 promotes ubi ...... plasma membrane ATPase, PMA1.
@en
Cytoplasmic Hsp70 promotes ubi ...... plasma membrane ATPase, PMA1.
@nl
type
label
Cytoplasmic Hsp70 promotes ubi ...... plasma membrane ATPase, PMA1.
@en
Cytoplasmic Hsp70 promotes ubi ...... plasma membrane ATPase, PMA1.
@nl
prefLabel
Cytoplasmic Hsp70 promotes ubi ...... plasma membrane ATPase, PMA1.
@en
Cytoplasmic Hsp70 promotes ubi ...... plasma membrane ATPase, PMA1.
@nl
P2093
P2860
P356
P1476
Cytoplasmic Hsp70 promotes ubi ...... plasma membrane ATPase, PMA1.
@en
P2093
P2860
P304
26140-26149
P356
10.1074/JBC.M701969200
P407
P577
2007-07-13T00:00:00Z