Geometrically and conformationally restrained cinnamoyl compounds as inhibitors of HIV-1 integrase: synthesis, biological evaluation, and molecular modeling.
about
CLEFMA-an anti-proliferative curcuminoid from structure-activity relationship studies on 3,5-bis(benzylidene)-4-piperidones.Novel paradigms for drug discovery: computational multitarget screeningTargeting Tn5 transposase identifies human immunodeficiency virus type 1 inhibitors.Identification of a key target sequence to block human immunodeficiency virus type 1 replication within the gag-pol transframe domain.Novel compounds in preclinical/early clinical development for the treatment of HIV infections.Recent progress in pharmacological research of propolis.On the Importance of the Aromatic Ring Parameter in Studies of the Solvolyses of Cinnamyl and Cinnamoyl Halides.Biological properties of curcumin-cellular and molecular mechanisms of action.Recent advances in the investigation of curcuminoids.Novel bifunctional quinolonyl diketo acid derivatives as HIV-1 integrase inhibitors: design, synthesis, biological activities, and mechanism of actionRecent progress in therapeutic applications of chalcones.Conformational restriction: an effective tactic in 'follow-on'-based drug discovery.Synthesis, spectroscopic investigations (X-ray, NMR and TD-DFT), antimicrobial activity and molecular docking of 2,6-bis(hydroxy(phenyl)methyl)cyclohexanone.Synthesis and anti-tumor activity of novel aminomethylated derivatives of isoliquiritigenin.Inhibiting the HIV integration process: past, present, and the future.Support Vector Machine (SVM) Models for Predicting Inhibitors of the 3' Processing Step of HIV-1 Integrase.New anti-human immunodeficiency virus type 1 6-aminoquinolones: mechanism of action.Synthesis of prodrug-type anti-HIV agents conjugating a REVERSE transcriptase inhibitor to a HIV-1 integrase inhibitor by a spontaneously cleavable linker.Structure-Activity Relationships on Cinnamoyl Derivatives as Inhibitors of p300 Histone Acetyltransferase.A high-throughput assay for Tn5 Tnp-induced DNA cleavage.Computational models on quantitative prediction of bioactivity of HIV-1 integrase 3' processing inhibitors.Curcuminoid-BF2 complexes: Synthesis, fluorescence and optimization of BF2 group cleavage.Effect of alicyclic ring size on the photophysical and photochemical properties of bis(arylidene)cycloalkanone compounds.Inhibitor of CBP Histone Acetyltransferase Downregulates p53 Activation and Facilitates Methylation at Lysine 27 on Histone H3
P2860
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P2860
Geometrically and conformationally restrained cinnamoyl compounds as inhibitors of HIV-1 integrase: synthesis, biological evaluation, and molecular modeling.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Geometrically and conformation ...... ation, and molecular modeling.
@en
Geometrically and conformation ...... ation, and molecular modeling.
@nl
type
label
Geometrically and conformation ...... ation, and molecular modeling.
@en
Geometrically and conformation ...... ation, and molecular modeling.
@nl
prefLabel
Geometrically and conformation ...... ation, and molecular modeling.
@en
Geometrically and conformation ...... ation, and molecular modeling.
@nl
P2093
P50
P356
P1476
Geometrically and conformation ...... uation, and molecular modeling
@en
P2093
P304
P356
10.1021/JM9707232
P407
P577
1998-10-01T00:00:00Z