Impaired TIP60-mediated H4K16 acetylation accounts for the aberrant chromatin accumulation of 53BP1 and RAP80 in Fanconi anemia pathway-deficient cells.
about
Chronic treatment with cisplatin induces chemoresistance through the TIP60-mediated Fanconi anemia and homologous recombination repair pathways.Maintenance of genome stability by Fanconi anemia proteins.E3 ligase UHRF2 stabilizes the acetyltransferase TIP60 and regulates H3K9ac and H3K14ac via RING finger domain.Ammonium tetrathiomolybdate treatment targets the copper transporter ATP7A and enhances sensitivity of breast cancer to cisplatinPRMT5-Dependent Methylation of the TIP60 Coactivator RUVBL1 Is a Key Regulator of Homologous Recombination.Cross-talk between the H3K36me3 and H4K16ac histone epigenetic marks in DNA double-strand break repair.The adenoviral E1A N-terminal domain represses MYC transcription in human cancer cells by targeting both p300 and TRRAP and inhibiting MYC promoter acetylation of H3K18 and H4K16.Fanconi Anemia: A DNA repair disorder characterized by accelerated decline of the hematopoietic stem cell compartment and other features of aging.Factors forming the BRCA1-A complex orchestrate BRCA1 recruitment to the sites of DNA damage.Mechanisms of DNA damage, repair, and mutagenesis.Emerging functions of the Fanconi anemia pathway at a glance.V(D)J recombination process and the Pre-B to immature B-cells transition are altered in Fanca(-/-) mice.Interaction of the epigenetic integrator UHRF1 with the MYST domain of TIP60 inside the cell.Acetylation of 53BP1 dictates the DNA double strand break repair pathway.Reduced recruitment of 53BP1 during interstrand crosslink repair is associated with genetically inherited attenuation of mitomycin C sensitivity in a family with Fanconi anemia.Extra View: Sirt1 Acts As A Gatekeeper Of Replication Initiation To Preserve Genomic Stability.The Nature of Actin-Family Proteins in Chromatin-Modifying ComplexesThe Cancer/Testes (CT) Antigen HORMAD1 promotes Homologous Recombinational DNA Repair and Radioresistance in Lung adenocarcinoma cells
P2860
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P2860
Impaired TIP60-mediated H4K16 acetylation accounts for the aberrant chromatin accumulation of 53BP1 and RAP80 in Fanconi anemia pathway-deficient cells.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Impaired TIP60-mediated H4K16 ...... nemia pathway-deficient cells.
@en
Impaired TIP60-mediated H4K16 ...... nemia pathway-deficient cells.
@nl
type
label
Impaired TIP60-mediated H4K16 ...... nemia pathway-deficient cells.
@en
Impaired TIP60-mediated H4K16 ...... nemia pathway-deficient cells.
@nl
prefLabel
Impaired TIP60-mediated H4K16 ...... nemia pathway-deficient cells.
@en
Impaired TIP60-mediated H4K16 ...... nemia pathway-deficient cells.
@nl
P2093
P2860
P356
P1476
Impaired TIP60-mediated H4K16 ...... nemia pathway-deficient cells.
@en
P2093
Aurelia Barascu
Emilie Renaud
Filippo Rosselli
P2860
P304
P356
10.1093/NAR/GKV1019
P407
P577
2015-10-07T00:00:00Z