Discovery of ritonavir, a potent inhibitor of HIV protease with high oral bioavailability and clinical efficacy.
about
ABT-378, a highly potent inhibitor of the human immunodeficiency virus proteaseOptimization of metabolic stability as a goal of modern drug design.Structure-activity relationships for inhibition of cysteine protease activity and development of Plasmodium falciparum by peptidyl vinyl sulfones.Catalytic enantioselective hetero-Diels-Alder reactions of an azo compound.Thiazolidinone CFTR inhibitors with improved water solubility identified by structure-activity analysisTetrahydrofuran, tetrahydropyran, triazoles and related heterocyclic derivatives as HIV protease inhibitors.Ritonavir-boosted protease inhibitor based therapy: a new strategy in chronic hepatitis C therapy.Procathepsin E is highly abundant but minimally active in pancreatic ductal adenocarcinoma tumors.Quantitative structure-activity relationship of some HIV-1 protease inhibitors: a Fujita-Ban type analysis.Unusual phyletic distribution of peptidases as a tool for identifying potential drug targets.HIV protease inhibitor induces fatty acid and sterol biosynthesis in liver and adipose tissues due to the accumulation of activated sterol regulatory element-binding proteins in the nucleus.Overview of drug discovery and development.
P2860
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P2860
Discovery of ritonavir, a potent inhibitor of HIV protease with high oral bioavailability and clinical efficacy.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Discovery of ritonavir, a pote ...... ability and clinical efficacy.
@en
Discovery of ritonavir, a pote ...... ability and clinical efficacy.
@nl
type
label
Discovery of ritonavir, a pote ...... ability and clinical efficacy.
@en
Discovery of ritonavir, a pote ...... ability and clinical efficacy.
@nl
prefLabel
Discovery of ritonavir, a pote ...... ability and clinical efficacy.
@en
Discovery of ritonavir, a pote ...... ability and clinical efficacy.
@nl
P2093
P356
P1476
Discovery of ritonavir, a pote ...... ability and clinical efficacy.
@en
P2093
Betebenner D
Flentge CA
McDonald E
Norbeck DW
P304
P356
10.1021/JM970636+
P407
P577
1998-02-01T00:00:00Z