Wnt signaling mediates pathological vascular growth in proliferative retinopathy
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Critical Endothelial Regulation by LRP5 during Retinal Vascular DevelopmentMaternal anti-platelet β3 integrins impair angiogenesis and cause intracranial hemorrhage.Wnt signaling pathway in retinal vascularizationElevated circulation levels of an antiangiogenic SERPIN in patients with diabetic microvascular complications impair wound healing through suppression of Wnt signalingRetinal expression of Wnt-pathway mediated genes in low-density lipoprotein receptor-related protein 5 (Lrp5) knockout mice.LRP5 regulates development of lung microvessels and alveoli through the angiopoietin-Tie2 pathwayThe blood-brain barrier.Twist1 controls lung vascular permeability and endotoxin-induced pulmonary edema by altering Tie2 expression.Deletion of LRP5 in VLDLR knockout mice inhibits retinal neovascularization.Nrf2 acts cell-autonomously in endothelium to regulate tip cell formation and vascular branching.Kaposi's sarcoma-associated herpesvirus G-protein coupled receptor activates the canonical Wnt/β-catenin signaling pathway.Sirtuin1 over-expression does not impact retinal vascular and neuronal degeneration in a mouse model of oxygen-induced retinopathy.Nanoparticle-mediated expression of a Wnt pathway inhibitor ameliorates ocular neovascularizationWnting out ocular neovascularization: using nanoparticle delivery of very-low density lipoprotein receptor extracellular domain as Wnt pathway inhibitor in the retina.Elevated LRP6 levels correlate with vascular endothelial growth factor in the vitreous of proliferative diabetic retinopathy.Endothelial microRNA-150 is an intrinsic suppressor of pathologic ocular neovascularization.The peptidomimetic Vasotide targets two retinal VEGF receptors and reduces pathological angiogenesis in murine and nonhuman primate models of retinal disease.BMP9/ALK1 inhibits neovascularization in mouse models of age-related macular degeneration.Per2-Mediated Vascular Dysfunction Is Caused by the Upregulation of the Connective Tissue Growth Factor (CTGF).Using the past to inform the future: anti-VEGF therapy as a road map to develop novel therapies for diabetic retinopathyLgr4 in ocular development and glaucomaTCF7L2 variation and proliferative diabetic retinopathyNovel targets against retinal angiogenesis in diabetic retinopathy.Glial influence on the blood brain barrier.Next-generation sequencing analysis of gene regulation in the rat model of retinopathy of prematurity.Neurovascular cross talk in diabetic retinopathy: Pathophysiological roles and therapeutic implications.Animal models of ocular angiogenesis: from development to pathologies.Inflammatory signals from photoreceptor modulate pathological retinal angiogenesis via c-Fos.Functional Differences of Very-Low-Density Lipoprotein Receptor Splice Variants in Regulating Wnt Signaling.Pharmacologic Activation of Wnt Signaling by Lithium Normalizes Retinal Vasculature in a Murine Model of Familial Exudative Vitreoretinopathy.Endothelial adenosine A2a receptor-mediated glycolysis is essential for pathological retinal angiogenesis.Targeting WNT Signaling for Multifaceted Glioblastoma Therapy.Dkk1 and MSX2-Wnt7b signaling reciprocally regulate the endothelial-mesenchymal transition in aortic endothelial cells.Wnt4/β-catenin signaling pathway modulates balloon-injured carotid artery restenosis via disheveled-1.Canonical Wnt signaling induces vascular endothelial dysfunction via p66Shc-regulated reactive oxygen species.Suppression of corneal neovascularization by curcumin via inhibition of Wnt/β-catenin pathway activation.miR-200b downregulates Kruppel Like Factor 2 (KLF2) during acute hypoxia in human endothelial cells.Molecular Regulation of Sprouting Angiogenesis.Norrin stimulates cell proliferation in the superficial retinal vascular plexus and is pivotal for the recruitment of mural cells.MicroRNA and Microvascular Complications of Diabetes.
P2860
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P2860
Wnt signaling mediates pathological vascular growth in proliferative retinopathy
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Wnt signaling mediates pathological vascular growth in proliferative retinopathy
@en
Wnt signaling mediates pathological vascular growth in proliferative retinopathy
@nl
type
label
Wnt signaling mediates pathological vascular growth in proliferative retinopathy
@en
Wnt signaling mediates pathological vascular growth in proliferative retinopathy
@nl
prefLabel
Wnt signaling mediates pathological vascular growth in proliferative retinopathy
@en
Wnt signaling mediates pathological vascular growth in proliferative retinopathy
@nl
P2093
P2860
P1433
P1476
Wnt signaling mediates pathological vascular growth in proliferative retinopathy
@en
P2093
Aimee M Juan
Andreas Stahl
Christopher M Aderman
Colman J Hatton
Karen I Guerin
Keirnan L Willett
Lois E H Smith
Matthew Campbell
P2860
P304
P356
10.1161/CIRCULATIONAHA.111.040337
P407
P577
2011-10-03T00:00:00Z