Structure-Based Design of Type II Inhibitors Applied to Maternal Embryonic Leucine Zipper Kinase
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Perspective on computational and structural aspects of kinase discovery from IPK2014MELK: a potential novel therapeutic target for TNBC and other aggressive malignancies.Lead Discovery of Type II BRAF V600E Inhibitors Targeting the Structurally Validated DFG-Out Conformation Based upon Selected Fragments.CRISPR/Cas9 mutagenesis invalidates a putative cancer dependency targeted in on-going clinical trials.Considerations of Protein Subpockets in Fragment-Based Drug Design.Screening of a Novel Fragment Library with Functional Complexity against Mycobacterium tuberculosis InhA.
P2860
Structure-Based Design of Type II Inhibitors Applied to Maternal Embryonic Leucine Zipper Kinase
description
2014 nî lūn-bûn
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2014年の論文
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2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
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2014年论文
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2014年论文
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name
Structure-Based Design of Type ...... mbryonic Leucine Zipper Kinase
@en
Structure-Based Design of Type ...... mbryonic Leucine Zipper Kinase
@nl
type
label
Structure-Based Design of Type ...... mbryonic Leucine Zipper Kinase
@en
Structure-Based Design of Type ...... mbryonic Leucine Zipper Kinase
@nl
prefLabel
Structure-Based Design of Type ...... mbryonic Leucine Zipper Kinase
@en
Structure-Based Design of Type ...... mbryonic Leucine Zipper Kinase
@nl
P2093
P2860
P356
P1476
Structure-Based Design of Type ...... mbryonic Leucine Zipper Kinase
@en
P2093
Christophe Adelinet
Christopher C F Hamlett
David C Rees
Dirk Brehmer
Eddy J E Freyne
Elisabeth Pasquier
Frederick Calo
Joannes T M Linders
Joseph E Coyle
Laurence Mevellec
P2860
P356
10.1021/ML5001273
P577
2014-05-23T00:00:00Z