Insight into the mechanism of inactivation of ribonucleotide reductase by gemcitabine 5'-diphosphate in the presence or absence of reductant.
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Proton-coupled electron transferKinetics of Radical Intermediate Formation and Deoxynucleotide Production in 3-Aminotyrosine-Substituted Escherichia coli Ribonucleotide ReductasesTangled up in knots: structures of inactivated forms of E. coli class Ia ribonucleotide reductaseAlgorithmic modeling quantifies the complementary contribution of metabolic inhibitions to gemcitabine efficacyThe structural basis for the allosteric regulation of ribonucleotide reductase.Inactivation of Lactobacillus leichmannii ribonucleotide reductase by 2',2'-difluoro-2'-deoxycytidine 5'-triphosphate: covalent modificationMechanism of inactivation of human ribonucleotide reductase with p53R2 by gemcitabine 5'-diphosphateOne-electron oxidation of gemcitabine and analogs: mechanism of formation of C3' and C2' sugar radicals.A kinome screen identifies checkpoint kinase 1 (CHK1) as a sensitizer for RRM1-dependent gemcitabine efficacy.Modulation of the ribonucleotide reductase M1-gemcitabine interaction in vivo by N-ethylmaleimide.Singlet Oxygen-Mediated Oxidation during UVA Radiation Alters the Dynamic of Genomic DNA Replication.Targeting ribonucleotide reductase for cancer therapy.Deoxyribonucleotide metabolism, mutagenesis and cancer.Potential biomarkers for sensitivity of gallbladder cancer cells to gemcitabineSynthesis and cytostatic evaluation of 4-N-alkanoyl and 4-N-alkyl gemcitabine analogues.Human pyrimidine nucleotide biosynthesis as a target for antiviral chemotherapy.Reverse Electron Transfer Completes the Catalytic Cycle in a 2,3,5-Trifluorotyrosine-Substituted Ribonucleotide Reductase.Inactivation of Lactobacillus leichmannii ribonucleotide reductase by 2',2'-difluoro-2'-deoxycytidine 5'-triphosphate: adenosylcobalamin destruction and formation of a nucleotide-based radical.Relationship between electrochemical potentials and substitution reaction rates of ferrocene-containing β-diketonato rhodium(I) complexes; cytotoxicity of [Rh(FcCOCHCOPh)(cod)].Phylogenetic sequence analysis and functional studies reveal compensatory amino acid substitutions in loop 2 of human ribonucleotide reductase.The 4-N-acyl and 4-N-alkyl gemcitabine analogues with silicon-fluoride-acceptor: Application to 18F-Radiolabeling.
P2860
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P2860
Insight into the mechanism of inactivation of ribonucleotide reductase by gemcitabine 5'-diphosphate in the presence or absence of reductant.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Insight into the mechanism of ...... sence or absence of reductant.
@en
Insight into the mechanism of ...... sence or absence of reductant.
@nl
type
label
Insight into the mechanism of ...... sence or absence of reductant.
@en
Insight into the mechanism of ...... sence or absence of reductant.
@nl
prefLabel
Insight into the mechanism of ...... sence or absence of reductant.
@en
Insight into the mechanism of ...... sence or absence of reductant.
@nl
P2093
P2860
P356
P1433
P1476
Insight into the mechanism of ...... sence or absence of reductant.
@en
P2093
Erin Artin
Gregory J S Lohman
Kenichi Yokoyama
Robert G Griffin
P2860
P304
11622-11629
P356
10.1021/BI901590Q
P407
P577
2009-12-01T00:00:00Z