A C-terminal domain targets the Pseudomonas aeruginosa cytotoxin ExoU to the plasma membrane of host cells.
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Exploitation of eukaryotic subcellular targeting mechanisms by bacterial effectorsAssociation between Pseudomonas aeruginosa type III secretion, antibiotic resistance, and clinical outcome: a reviewIntoxication of host cells by the T3SS phospholipase ExoU: PI(4,5)P2-associated, cytoskeletal collapse and late phase membrane blebbingStructural basis of cytotoxicity mediated by the type III secretion toxin ExoU from Pseudomonas aeruginosaStructure of the Type III Secretion Effector Protein ExoU in Complex with Its Chaperone SpcUCooperative Substrate-Cofactor Interactions and Membrane Localization of the Bacterial Phospholipase A2 (PLA2) Enzyme, ExoU.Activation of ExoU phospholipase activity requires specific C-terminal regions.A sensitive fluorescence-based assay for the detection of ExoU-mediated PLA(2) activity.Pseudomonas aeruginosa cytotoxin ExoU is injected into phagocytic cells during acute pneumonia.Functional characterization of a phospholipase A(2) homolog from Rickettsia typhi.Role of the membrane localization domain of the Pseudomonas aeruginosa effector protein ExoU in cytotoxicityInduced conformational changes in the activation of the Pseudomonas aeruginosa type III toxin, ExoU.A novel phosphatidylinositol 4,5-bisphosphate binding domain mediates plasma membrane localization of ExoU and other patatin-like phospholipases.Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome.Phosphatidylinositol 4,5-bisphosphate is a novel coactivator of the Pseudomonas aeruginosa cytotoxin ExoU.Common themes in the design and function of bacterial effectors.Pseudomonas aeruginosa virulence and therapy: evolving translational strategies.The type III secretion system of Pseudomonas aeruginosa: infection by injection.Functional domains and motifs of bacterial type III effector proteins and their roles in infection.Bacterial toxin effector-membrane targeting: outside in, then back again.Structure and function of the Type III secretion system of Pseudomonas aeruginosa.Central role of PAFR signalling in ExoU-induced NF-κB activation.Phosphatidylinositol 4,5-bisphosphate-dependent Oligomerization of the Pseudomonas aeruginosa Cytotoxin ExoU.Identification and characterization of a phospholipase A1 activity type three secreted protein, PP_ExoU from Pseudomonas plecoglossicida NB2011, the causative agent of visceral granulomas disease in large yellow croaker (Larimichthys crocea).Intracellular Localization of Type III-deliveredPseudomonasExoS with Endosome Vesicles
P2860
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P2860
A C-terminal domain targets the Pseudomonas aeruginosa cytotoxin ExoU to the plasma membrane of host cells.
description
2006 nî lūn-bûn
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2006年の論文
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2006年論文
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2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
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2006年論文
@zh-tw
2006年论文
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2006年论文
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2006年论文
@zh-cn
name
A C-terminal domain targets th ...... plasma membrane of host cells.
@en
A C-terminal domain targets th ...... plasma membrane of host cells.
@nl
type
label
A C-terminal domain targets th ...... plasma membrane of host cells.
@en
A C-terminal domain targets th ...... plasma membrane of host cells.
@nl
prefLabel
A C-terminal domain targets th ...... plasma membrane of host cells.
@en
A C-terminal domain targets th ...... plasma membrane of host cells.
@nl
P2093
P2860
P1476
A C-terminal domain targets th ...... plasma membrane of host cells.
@en
P2093
Alan R Hauser
Jeffrey L Veesenmeyer
Kathryn T Bieging
Shira D P Rabin
P2860
P304
P356
10.1128/IAI.74.5.2552-2561.2006
P407
P577
2006-05-01T00:00:00Z