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Nanotopographic substrates of poly (methyl methacrylate) do not strongly influence the osteogenic phenotype of mesenchymal stem cells in vitroEffects of ultrasound frequency and tissue stiffness on the histotripsy intrinsic threshold for cavitation.Effects of tissue stiffness, ultrasound frequency, and pressure on histotripsy-induced cavitation bubble behaviorRecreating the perivascular niche ex vivo using a microfluidic approach.Engineering microscale cellular niches for three-dimensional multicellular co-culturesMatrix identity and tractional forces influence indirect cardiac reprogrammingEndothelial cell traction and ECM density influence both capillary morphogenesis and maintenance in 3-D.Extracellular matrix remodeling, integrin expression, and downstream signaling pathways influence the osteogenic differentiation of mesenchymal stem cells on poly(lactide-co-glycolide) substrates.Effects of hydroxyapatite on endothelial network formation in collagen/fibrin composite hydrogels in vitro and in vivo.Mesenchymal cells stimulate capillary morphogenesis via distinct proteolytic mechanisms.Assessing the permeability of engineered capillary networks in a 3D cultureVasculogenesis and Angiogenesis in Modular Collagen-Fibrin Microtissues.Overexpression of sprouty 2 inhibits HGF/SF-mediated cell growth, invasion, migration, and cytokinesis.Protease-sensitive PEG hydrogels regulate vascularization in vitro and in vivo.Extracellular matrix elasticity and topography: material-based cues that affect cell function via conserved mechanismsThe Instructive Role of the Vasculature in Stem Cell Niches.Dual-phase osteogenic and vasculogenic engineered tissue for bone formation.Bone marrow stromal cells stimulate an angiogenic program that requires endothelial MT1-MMP.Stromal cell identity influences the in vivo functionality of engineered capillary networks formed by co-delivery of endothelial cells and stromal cells.The emergence of ECM mechanics and cytoskeletal tension as important regulators of cell function.MT1-MMP-dependent control of skeletal stem cell commitment via a β1-integrin/YAP/TAZ signaling axis.Capillary morphogenesis in PEG-collagen hydrogelsBone marrow-derived mesenchymal stem cells enhance angiogenesis via their α6β1 integrin receptor.Sculpting the blank slate: how fibrin's support of vascularization can inspire biomaterial designStem cells derived from tooth periodontal ligament enhance functional angiogenesis by endothelial cells.Effects of extracellular matrix density and mesenchymal stem cells on neovascularization in vivo.The effects of matrix stiffness and RhoA on the phenotypic plasticity of smooth muscle cells in a 3-D biosynthetic hydrogel system.Intrinsic mechanical properties of the extracellular matrix affect the behavior of pre-osteoblastic MC3T3-E1 cells.Aqueous two-phase printing of cell-containing contractile collagen microgels.Mechanical strain controls endothelial patterning during angiogenic sprouting.The regulation of osteogenesis by ECM rigidity in MC3T3-E1 cells requires MAPK activation.The influence of ascorbic acid, TGF-beta1, and cell-mediated remodeling on the bulk mechanical properties of 3-D PEG-fibrinogen constructs.Optimizing seeding and culture methods to engineer smooth muscle tissue on biodegradable polymer matrices.Extracellular matrix rigidity governs smooth muscle cell motility in a biphasic fashion.A novel time-varying poly lactic-co glycolic acid external sheath for vein grafts designed under physiological loading.The use of poly(ethylene glycol) hydrogels to investigate the impact of ECM chemistry and mechanics on smooth muscle cells.Vitronectin and collagen I differentially regulate osteogenesis in mesenchymal stem cells.A novel three-dimensional model to quantify metastatic melanoma invasion.Mesenchymal stem cells enhance angiogenesis in mechanically viable prevascularized tissues via early matrix metalloproteinase upregulation.Evaluating the potential of endothelial cells derived from human induced pluripotent stem cells to form microvascular networks in 3D cultures.
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Andrew J Putnam
@ast
Andrew J Putnam
@en
Andrew J Putnam
@es
Andrew J Putnam
@nl
type
label
Andrew J Putnam
@ast
Andrew J Putnam
@en
Andrew J Putnam
@es
Andrew J Putnam
@nl
prefLabel
Andrew J Putnam
@ast
Andrew J Putnam
@en
Andrew J Putnam
@es
Andrew J Putnam
@nl
P106
P21
P31
P496
0000-0002-1262-4377