Alteration of Ca2+ permeability and sensitivity to Mg2+ and channel blockers by a single amino acid substitution in the N-methyl-D-aspartate receptor.
about
Enhanced ethanol inhibition of recombinant N-methyl-D-aspartate receptors by magnesium: role of NR3A subunitsGlutamate receptor poresAdjacent asparagines in the NR2-subunit of the NMDA receptor channel control the voltage-dependent block by extracellular Mg2+.High-affinity Zn block in recombinant N-methyl-D-aspartate receptors with cysteine substitutions at the Q/R/N site.How Nox2-containing NADPH oxidase affects cortical circuits in the NMDA receptor antagonist model of schizophrenia.Residues at the tip of the pore loop of NR3B-containing NMDA receptors determine Ca2+ permeability and Mg2+ block.Interaction of the NMDA receptor noncompetitive antagonist MK-801 with model and native membranes.Molecular design of the N-methyl-D-aspartate receptor binding site for phencyclidine and dizolcipine.A single tryptophan on M2 of glutamate receptor channels confers high permeability to divalent cations.Grin1 receptor deletion within CRF neurons enhances fear memoryRetrieval-induced NMDA receptor-dependent Arc expression in two models of cocaine-cue memory.Interactions between two divalent ion binding sites in N-methyl-D-aspartate receptor channelsMutations within the selectivity filter of the NMDA receptor-channel influence voltage dependent block by 5-hydroxytryptamine.Differential binding properties of [3H]dextrorphan and [3H]MK-801 in heterologously expressed NMDA receptors.Single-channel currents from diethylpyrocarbonate-modified NMDA receptors in cultured rat brain cortical neurons.Subconductance states of a mutant NMDA receptor channel kinetics, calcium, and voltage dependence.Conversion of functional synapses into silent synapses in the trigeminal brainstem after neonatal peripheral nerve transection.Calcium permeability of the N-methyl-D-aspartate receptor channel in hippocampal neurons in cultureSynthesis and structure activity relationship of tetrahydroisoquinoline-based potentiators of GluN2C and GluN2D containing N-methyl-D-aspartate receptorsA mutation that alters magnesium block of N-methyl-D-aspartate receptor channelsProbing the pore region of recombinant N-methyl-D-aspartate channels using external and internal magnesium blockCommon influences of non-competitive NMDA receptor antagonists on the consolidation and reconsolidation of cocaine-cue memory.Functional analysis of a de novo GRIN2A missense mutation associated with early-onset epileptic encephalopathy.Synaptic neurotransmitter-gated receptorsInfluence of GluN2 subunit identity on NMDA receptor function.Binding of ArgTX-636 in the NMDA receptor ion channelInternal Mg2+ block of recombinant NMDA channels mutated within the selectivity filter and expressed in Xenopus oocytes.NR2 subunit-dependence of NMDA receptor channel block by external Mg2+.Intracellular Mg2+ interacts with structural determinants of the narrow constriction contributed by the NR1-subunit in the NMDA receptor channel.The effects of BTS 54,505, a metabolite of sibutramine, on monoamine and excitatory amino acid-evoked responses in the rat dorsolateral geniculate nucleus in vivo.Zinc effects on NMDA receptor gating kinetics.Voltage-dependent interaction of open-channel blocking molecules with gating of NMDA receptors in rat cortical neurons.Ionic flow enhances low-affinity binding: a revised mechanistic view into Mg2+ block of NMDA receptors.Mg2+ and memantine block of rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes.Disease-associated missense mutations in GluN2B subunit alter NMDA receptor ligand binding and ion channel properties.
P2860
Q24336440-734639CC-A776-4605-82B2-9E504D982B8DQ27021745-70C4EB1D-5709-4A52-A6AC-2BB37914FD4BQ27867707-A84D780D-2C82-4312-8CA9-FEAA799E22FDQ28367644-B6FD5AA5-27D6-4108-8A3D-295665F8F68AQ30439924-1C554246-AAEA-4ADC-BD0A-44281066E0BBQ33722699-7F48CF5E-BB7D-416D-BCE6-57CCE642F41CQ34019068-C74C859F-1367-4F5F-AEB9-3421E0E4E225Q34024207-48672349-63F6-4577-9CAB-0096845078C4Q34040307-463B66BF-E1D3-476A-960D-E706F5428BE1Q34395647-AF85639B-B795-403F-A845-2695D31C6B8CQ34674312-A6C70529-B1B8-4997-A148-3960F73AFB17Q35947358-657FE78E-7A60-46ED-A2BC-F6544EFB9FB8Q36052454-827184F0-6DDF-4D39-BAEB-FF21D60A36E8Q36303035-A3438266-CF1C-4DC2-98E8-9E815AA09908Q36411702-E07D8EC7-FDA6-4E26-839E-582462A0FD90Q36417599-D75985D3-6DC5-414B-A354-2530081D49E1Q36566559-4264242D-F17B-405E-8631-07889C5D47ADQ36714319-E566456E-F1BC-47BD-81CD-56A0423C5658Q36851341-EAE01034-D373-48A1-BF49-DCFA0B4686CCQ37391423-DB59ACEF-9908-4D2A-ACDC-0C3612D5D4F8Q37413971-5B1C9800-A2DF-4DC3-8314-DE8D76D620B0Q37568031-26BE5AC3-43C9-42CE-B61E-3A0B63E6A7A4Q37603368-69B0FAFC-8B03-49AC-8D20-AB70F02CEBB9Q37974718-576AE131-71EF-4F8D-8E2D-CD0305B8C1D3Q38078685-F11BC0AC-0302-428E-B48B-84A9045F19CCQ39186423-00E54631-5224-43C4-90B9-DBF71C374767Q39449712-5526296A-B0FD-47CC-9D6E-0F87387AE2A1Q40498654-CB6890DD-96F4-4CDD-A09C-A9CED6D6EBABQ41063217-6E0182B9-052F-45DD-8D02-433F0EC943D8Q41897251-3B6C7076-C10D-417D-8299-1633D9CE8A1EQ42598082-A80C69D4-730A-4C10-8EDA-7F06C8C0FC88Q42637358-D0AEE94A-EC43-4BE4-A86C-7B57125F3957Q43212365-E51F0156-AAFA-4242-80C9-F02EDEBB8AABQ46930523-F8DF8FA2-7417-4D0E-A334-C3CFB5099C99Q50418409-115F9973-C2F6-49BE-85E9-63BDBA235E7E
P2860
Alteration of Ca2+ permeability and sensitivity to Mg2+ and channel blockers by a single amino acid substitution in the N-methyl-D-aspartate receptor.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Alteration of Ca2+ permeabilit ...... N-methyl-D-aspartate receptor.
@en
Alteration of Ca2+ permeabilit ...... N-methyl-D-aspartate receptor.
@nl
type
label
Alteration of Ca2+ permeabilit ...... N-methyl-D-aspartate receptor.
@en
Alteration of Ca2+ permeabilit ...... N-methyl-D-aspartate receptor.
@nl
prefLabel
Alteration of Ca2+ permeabilit ...... N-methyl-D-aspartate receptor.
@en
Alteration of Ca2+ permeabilit ...... N-methyl-D-aspartate receptor.
@nl
P2093
P1476
Alteration of Ca2+ permeabilit ...... N-methyl-D-aspartate receptor
@en
P2093
P304
P407
P577
1993-01-01T00:00:00Z