The hepatitis B virus X gene potentiates c-myc-induced liver oncogenesis in transgenic mice.
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Hepatitis B virus X protein upregulates HSP90alpha expression via activation of c-Myc in human hepatocarcinoma cell line, HepG2RMP, a novel RNA polymerase II subunit 5-interacting protein, counteracts transactivation by hepatitis B virus X proteinHepatitis B virus-X protein upregulates the expression of p21waf1/cip1 and prolongs G1-->S transition via a p53-independent pathway in human hepatoma cellsThe X protein of hepatitis B virus binds to the F box protein Skp2 and inhibits the ubiquitination and proteasomal degradation of c-MycAkt augments the oncogenic potential of the HBx protein of hepatitis B virus by phosphorylationThe enigmatic X gene of hepatitis B virusHepatitis B virus HBx protein sensitizes cells to apoptotic killing by tumor necrosis factor alphaMouse models in liver cancer research: A review of current literatureEffects of antiviral therapy on preventing liver tumorigenesis and hepatocellular carcinoma recurrence.Molecular biology of hepatitis B virus infectionRadio-deoxynucleoside Analogs used for Imaging tk Expression in a Transgenic Mouse Model of Induced Hepatocellular Carcinoma.Hepatitis B virus X protein overcomes oncogenic RAS-induced senescence in human immortalized cells.Transformation of human liver L-O2 cells mediated by stable HBx transfection.c-MYC-Making Liver Sick: Role of c-MYC in Hepatic Cell Function, Homeostasis and Disease.Involvement of DNA damage response pathways in hepatocellular carcinoma.MicroRNAs as therapeutic strategy for hepatitis B virus-associated hepatocellular carcinoma: current status and future prospectsMolecular genetics of hepatocellular neoplasia.Human hepatitis B virus mutants: significance of molecular changes.Hepatitis B virus X protein interferes with cellular DNA repair.Expression of hepatitis B virus X protein does not alter the accumulation of spontaneous mutations in transgenic miceClinical implications of hepatitis B virus mutations: recent advances.Role of NF-kappaB and myc proteins in apoptosis induced by hepatitis B virus HBx protein.Hepatitis B virus X protein impedes the DNA repair via its association with transcription factor, TFIIHReview of hepatocellular carcinoma: Epidemiology, etiology, and carcinogenesisHepatitis B virus biology.Molecular Pathogenesis of Hepatitis-B-virus-associated Hepatocellular Carcinoma.Proteins ZNF198 and SUZ12 are down-regulated in hepatitis B virus (HBV) X protein-mediated hepatocyte transformation and in HBV replicationPutative role of hepatitis B virus X protein in hepatocarcinogenesis: effects on apoptosis, DNA repair, mitogen-activated protein kinase and JAK/STAT pathways.Paracrine in vivo inhibitory effects of hepatitis B virus X protein (HBx) on liver cell proliferation: an alternative mechanism of HBx-related pathogenesisInteraction of Hepatitis B virus with cellular processes in liver carcinogenesis.Modulation of miR-29 expression by α-fetoprotein is linked to the hepatocellular carcinoma epigenome.TGF-β/Smad signaling during hepatic fibro-carcinogenesis (review).Polo-like kinase 1 activated by the hepatitis B virus X protein attenuates both the DNA damage checkpoint and DNA repair resulting in partial polyploidyThe woodchuck model of hepatitis B virus infection.Study of PTPC composition during apoptosis for identification of viral protein target.The effect of miR-338-3p on HBx deletion-mutant (HBx-d382) mediated liver-cell proliferation through CyclinD1 regulationTargeting c-Myc as a novel approach for hepatocellular carcinoma.The hepatitis B virus X protein sensitizes HepG2 cells to UV light-induced DNA damage.Hepatitis B and C virus hepatocarcinogenesis: lessons learned and future challenges.Tumor necrosis factor alpha inhibition of hepatitis B virus replication involves disruption of capsid Integrity through activation of NF-kappaB.
P2860
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P2860
The hepatitis B virus X gene potentiates c-myc-induced liver oncogenesis in transgenic mice.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
The hepatitis B virus X gene p ...... ncogenesis in transgenic mice.
@en
The hepatitis B virus X gene p ...... ncogenesis in transgenic mice.
@nl
type
label
The hepatitis B virus X gene p ...... ncogenesis in transgenic mice.
@en
The hepatitis B virus X gene p ...... ncogenesis in transgenic mice.
@nl
prefLabel
The hepatitis B virus X gene p ...... ncogenesis in transgenic mice.
@en
The hepatitis B virus X gene p ...... ncogenesis in transgenic mice.
@nl
P2093
P356
P1433
P1476
The hepatitis B virus X gene p ...... ncogenesis in transgenic mice.
@en
P2093
Buendia MA
Terradillos O
P2888
P304
P356
10.1038/SJ.ONC.1200850
P407
P577
1997-01-01T00:00:00Z
P5875
P6179
1029444761