Maurocalcine and peptide A stabilize distinct subconductance states of ryanodine receptor type 1, revealing a proportional gating mechanism.
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Molecular basis of the high-affinity activation of type 1 ryanodine receptors by imperatoxin AMultiple loops of the dihydropyridine receptor pore subunit are required for full-scale excitation-contraction coupling in skeletal muscle.Multiple actions of phi-LITX-Lw1a on ryanodine receptors reveal a functional link between scorpion DDH and ICK toxins.Transient loss of voltage control of Ca2+ release in the presence of maurocalcine in skeletal muscle.The elusive role of the SPRY2 domain in RyR1.Rem uncouples excitation-contraction coupling in adult skeletal muscle fibers.Structure-function relationships of peptides forming the calcin family of ryanodine receptor ligands.In cellulo phosphorylation induces pharmacological reprogramming of maurocalcin, a cell-penetrating venom peptideCharged surface area of maurocalcine determines its interaction with the skeletal ryanodine receptor.Direct peptide interaction with surface glycosaminoglycans contributes to the cell penetration of maurocalcine.Ryanoids and imperatoxin affect the modulation of cardiac ryanodine receptors by dihydropyridine receptor Peptide A.Both basic and acidic amino acid residues of IpTx(a) are involved in triggering substate of RyR1.Transduction of the scorpion toxin maurocalcine into cells. Evidence that the toxin crosses the plasma membraneCell penetration properties of a highly efficient mini maurocalcine PeptideHemicalcin, a new toxin from the Iranian scorpion Hemiscorpius lepturus which is active on ryanodine-sensitive Ca2+ channelsMaurocalcine and domain A of the II-III loop of the dihydropyridine receptor Cav 1.1 subunit share common binding sites on the skeletal ryanodine receptor.Ryanodine receptor type 1 (RyR1) possessing malignant hyperthermia mutation R615C exhibits heightened sensitivity to dysregulation by non-coplanar 2,2',3,5',6-pentachlorobiphenyl (PCB 95).Small efficient cell-penetrating peptides derived from scorpion toxin maurocalcineD-Maurocalcine, a pharmacologically inert efficient cell-penetrating peptide analoguePeptide fragments of the dihydropyridine receptor can modulate cardiac ryanodine receptor channel activity and sarcoplasmic reticulum Ca2+ release.Critical amino acid residues determine the binding affinity and the Ca2+ release efficacy of maurocalcine in skeletal muscle cells.Multiple actions of imperatoxin A on ryanodine receptors: interactions with the II-III loop "A" fragment.Differential effects of maurocalcine on Ca2+ release events and depolarization-induced Ca2+ release in rat skeletal muscle.Association of FK506 binding proteins with RyR channels - effect of CLIC2 binding on sub-conductance opening and FKBP binding.Lanthanides Report Calcium Sensor in the Vestibule of Ryanodine Receptor.Recombinant expression of Intrepicalcin from the scorpion Vaejovis intrepidus and its effect on skeletal ryanodine receptors.
P2860
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P2860
Maurocalcine and peptide A stabilize distinct subconductance states of ryanodine receptor type 1, revealing a proportional gating mechanism.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
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2003年论文
@zh-cn
name
Maurocalcine and peptide A sta ...... proportional gating mechanism.
@en
Maurocalcine and peptide A sta ...... proportional gating mechanism.
@nl
type
label
Maurocalcine and peptide A sta ...... proportional gating mechanism.
@en
Maurocalcine and peptide A sta ...... proportional gating mechanism.
@nl
prefLabel
Maurocalcine and peptide A sta ...... proportional gating mechanism.
@en
Maurocalcine and peptide A sta ...... proportional gating mechanism.
@nl
P2093
P2860
P356
P1476
Maurocalcine and peptide A sta ...... proportional gating mechanism
@en
P2093
Eric Estève
Isaac N Pessah
Michel Ronjat
Paul D Allen
P2860
P304
16095-16106
P356
10.1074/JBC.M209501200
P407
P577
2003-02-13T00:00:00Z