The γH2AX assay for genotoxic and nongenotoxic agents: comparison of H2AX phosphorylation with cell death response.
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High-Content Analysis Provides Mechanistic Insights into the Testicular Toxicity of Bisphenol A and Selected Analogues in Mouse Spermatogonial CellsHigh-throughput imaging-based nephrotoxicity prediction for xenobiotics with diverse chemical structuresWee1 inhibition potentiates Wip1-dependent p53-negative tumor cell death during chemotherapyThe Brassica-derived phytochemical indolo[3,2-b]carbazole protects against oxidative DNA damage by aryl hydrocarbon receptor activation.Molecular pathway of near-infrared laser phototoxicity involves ATF-4 orchestrated ER stressIdentification of genotoxic compounds using isogenic DNA repair deficient DT40 cell lines on a quantitative high throughput screening platform.Low Dose Iron Treatments Induce a DNA Damage Response in Human Endothelial Cells within MinutesDNA double-strand break repair: a theoretical framework and its application.Genotoxic mode of action predictions from a multiplexed flow cytometric assay and a machine learning approach.Evaluation of surrogate tissues as indicators of drug activity in a melanoma skin modelDNA Damage Detection by 53BP1: Relationship to Species Longevity.Convergent adaptation of cellular machineries in the evolution of large body masses and long life spans.γH2AX and p53 responses in TK6 cells discriminate promutagens and nongenotoxicants in the presence of rat liver S9.The γH2AX DNA damage assay from a drop of blood.Complementarity of phosphorylated histones H2AX and H3 quantification in different cell lines for genotoxicity screening.Evaluation of four human cell lines with distinct biotransformation properties for genotoxic screening.Interlaboratory evaluation of a multiplexed high information content in vitro genotoxicity assay.The catalytic topoisomerase II inhibitor dexrazoxane induces DNA breaks, ATF3 and the DNA damage response in cancer cells.A proposal for a novel rationale for critical effect size in dose-response analysis based on a multi-endpoint in vivo study with methyl methanesulfonate.Analysis of the interplay between all-trans retinoic acid and histone deacetylase inhibitors in leukemic cells.Effects of antifreeze proteins on the vitrification of mouse oocytes: comparison of three different antifreeze proteins.γH2AX assay as DNA damage biomarker for human population studies: defining experimental conditions.Early Detection of Genotoxic Urinary Bladder Carcinogens by Immunohistochemistry for γ-H2AX.Investigating the Generalizability of the MultiFlow® DNA Damage Assay and Several Companion Machine Learning Models with a Set of 103 Diverse Test Chemicals.Evaluating the evidence on genotoxicity and reproductive toxicity of carbon black: a critical review.Potential role of the mitochondria as a target for the hepatotoxic effects of (-)-epigallocatechin-3-gallate in mice.Perinatal Exposure to the Cyanotoxin β-N-Méthylamino-L-Alanine (BMAA) Results in Long-Lasting Behavioral Changes in Offspring-Potential Involvement of DNA Damage and Oxidative Stress.Classification of in vitro genotoxicants using a novel multiplexed biomarker assay compared to the flow cytometric micronucleus test.In vitro effects of two silicate-based materials, Biodentine and BioRoot RCS, on dental pulp stem cells in models of reactionary and reparative dentinogenesis.γ-H2AX formation in the urinary bladder of rats treated with two norharman derivatives obtained from o-toluidine and aniline.Assessment of the DNA damaging potential of environmental chemicals using a quantitative high-throughput screening approach to measure p53 activation.toxicity evaluation of silica-coated iron oxide nanoparticles in human SHSY5Y neuronal cells
P2860
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P2860
The γH2AX assay for genotoxic and nongenotoxic agents: comparison of H2AX phosphorylation with cell death response.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
The γH2AX assay for genotoxic ...... tion with cell death response.
@en
The γH2AX assay for genotoxic ...... tion with cell death response.
@nl
type
label
The γH2AX assay for genotoxic ...... tion with cell death response.
@en
The γH2AX assay for genotoxic ...... tion with cell death response.
@nl
prefLabel
The γH2AX assay for genotoxic ...... tion with cell death response.
@en
The γH2AX assay for genotoxic ...... tion with cell death response.
@nl
P2093
P2860
P356
P1476
The γH2AX assay for genotoxic ...... tion with cell death response.
@en
P2093
Aslihan Gerhold-Ay
Bernd Kaina
Elisabeth Krämer
Fabian Jung
Isabell Adam
Mirek Dvorak
Teodora Nikolova
P2860
P304
P356
10.1093/TOXSCI/KFU066
P577
2014-04-17T00:00:00Z