Rapid discovery of a novel series of Abl kinase inhibitors by application of an integrated microfluidic synthesis and screening platform.

Rapid discovery of a novel series of Abl kinase inhibitors by application of an integrated microfluidic synthesis and screening platform.

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http://www.wikidata.org/entity/Q42712714
The synthesis of active pharmaceutical ingredients (APIs) using continuous flow chemistryCurrent status and future prospects for enabling chemistry technology in the drug discovery processSeamless integration of dose-response screening and flow chemistry: efficient generation of structure-activity relationship data of β-secretase (BACE1) inhibitors.Integrated Platform for Expedited Synthesis-Purification-Testing of Small Molecule Libraries.Suzuki-Miyaura cross-coupling optimization enabled by automated feedback.Accessing new chemical entities through microfluidic systems.Microfluidics: reframing biological enquiry.Active learning for computational chemogenomics.Unlocking the potential benefits of flow chemistry in the drug-discovery process.Future De Novo Drug Design.Integrated Synthesis and Testing of Substituted Xanthine Based DPP4 Inhibitors: Application to Drug DiscoveryGeneration and Trapping of Ketenes in Flow.Proteomic analysis reveals distinctive protein profiles involved in CD8+ T cell-mediated murine autoimmune cholangitis.A segmented flow platform for on-demand medicinal chemistry and compound synthesis in oscillating droplets.Machine-assisted synthesis of modulators of the histone reader BRD9 using flow methods of chemistry and frontal affinity chromatographySynthesis, Structure and Antitumoural Activity of Triazole-Functionalised NHC-Metal Complexes
P2860

Rapid discovery of a novel series of Abl kinase inhibitors by application of an integrated microfluidic synthesis and screening platform.

Item
http://www.wikidata.org/entity/Q42712714
description
2013 nî lūn-bûn
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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2013年论文
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2013年论文
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name
Rapid discovery of a novel ser ...... thesis and screening platform.
@en
Rapid discovery of a novel ser ...... thesis and screening platform.
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type
label
Rapid discovery of a novel ser ...... thesis and screening platform.
@en
Rapid discovery of a novel ser ...... thesis and screening platform.
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prefLabel
Rapid discovery of a novel ser ...... thesis and screening platform.
@en
Rapid discovery of a novel ser ...... thesis and screening platform.
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P1433
P1476
Rapid discovery of a novel ser ...... nthesis and screening platform
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P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921