Sunitinib, a tyrosine kinase inhibitor, induces cytochrome P450 1A1 gene in human breast cancer MCF7 cells through ligand-independent aryl hydrocarbon receptor activation.

Sunitinib, a tyrosine kinase inhibitor, induces cytochrome P450 1A1 gene in human breast cancer MCF7 cells through ligand-independent aryl hydrocarbon receptor activation.

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http://www.wikidata.org/entity/Q42713524
Vatalanib population pharmacokinetics in patients with myelodysplastic syndrome: CALGB 10105 (Alliance)Activation of the aryl hydrocarbon receptor by the widely used Src family kinase inhibitor 4-amino-5-(4-chlorophenyl)-7-(dimethylethyl)pyrazolo[3,4-d]pyrimidine (PP2).Oestrogen enhances cardiotoxicity induced by Sunitinib by regulation of drug transport and metabolism.The role of cytochrome P450 1B1 and its associated mid-chain hydroxyeicosatetraenoic acid metabolites in the development of cardiac hypertrophy induced by isoproterenol.Mechanisms of xenobiotic receptor activation: Direct vs. indirect.Development of cellular hypertrophy by 8-hydroxyeicosatetraenoic acid in the human ventricular cardiomyocyte, RL-14 cell line, is implicated by MAPK and NF-κB.5-, 12- and 15-Hydroxyeicosatetraenoic acids induce cellular hypertrophy in the human ventricular cardiomyocyte, RL-14 cell line, through MAPK- and NF-κB-dependent mechanism.Development of cardiac hypertrophy by sunitinib in vivo and in vitro rat cardiomyocytes is influenced by the aryl hydrocarbon receptor signaling pathway.Mechanistically elucidating the in vitro safety and efficacy of a novel doxorubicin derivative.Genetic polymorphisms associated with adverse reactions of molecular-targeted therapies in renal cell carcinoma.2-Methoxyestradiol protects against pressure overload-induced left ventricular hypertrophy.Pharmacodynamic and Pharmacokinetic Markers For Anti-angiogenic Cancer Therapy: Implications for Dosing and Selection of Patients.Differential Effects of Sunitinib on the Expression Profiles of Xenobiotic-Metabolizing Enzymes and Transporters in Rat Liver and Kidneys.Commentary: Usage of Mitogen-Activated Protein Kinase Small Molecule Inhibitors: More Than Just Inhibition!DOX-Vit D, a Novel Doxorubicin Delivery Approach, Inhibits Human Osteosarcoma Cell Proliferation by Inducing Apoptosis While Inhibiting Akt and mTOR Signaling Pathways
P2860

Sunitinib, a tyrosine kinase inhibitor, induces cytochrome P450 1A1 gene in human breast cancer MCF7 cells through ligand-independent aryl hydrocarbon receptor activation.

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http://www.wikidata.org/entity/Q42713524
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2013 nî lūn-bûn
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name
Sunitinib, a tyrosine kinase i ...... drocarbon receptor activation.
@en
Sunitinib, a tyrosine kinase i ...... drocarbon receptor activation.
@nl
type
label
Sunitinib, a tyrosine kinase i ...... drocarbon receptor activation.
@en
Sunitinib, a tyrosine kinase i ...... drocarbon receptor activation.
@nl
prefLabel
Sunitinib, a tyrosine kinase i ...... drocarbon receptor activation.
@en
Sunitinib, a tyrosine kinase i ...... drocarbon receptor activation.
@nl
P1433
P1476
P2093
P2860
P2888
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P31
P356
P433
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P577
P698
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P1433
P1476
Sunitinib, a tyrosine kinase i ...... drocarbon receptor activation.
@en
P2093
P2860
P2888
P304
P31
P356
P433
P478
P577
P698