Simultaneous quantitation of IC87114, roflumilast and its active metabolite roflumilast N-oxide in plasma by LC-MS/MS: application for a pharmacokinetic study.

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Phosphoinositide 3-Kinase δ Regulates Dectin-2 Signaling and the Generation of Th2 and Th17 Immunity.Safety and Pharmacodynamics of the PDE4 Inhibitor Roflumilast in Advanced B-cell Malignancies.

P2860

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P2860

Simultaneous quantitation of IC87114, roflumilast and its active metabolite roflumilast N-oxide in plasma by LC-MS/MS: application for a pharmacokinetic study.

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2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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Simultaneous quantitation of I ...... n for a pharmacokinetic study.

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Simultaneous quantitation of I ...... n for a pharmacokinetic study.

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Simultaneous quantitation of I ...... n for a pharmacokinetic study.

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Simultaneous quantitation of I ...... n for a pharmacokinetic study.

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Simultaneous quantitation of I ...... n for a pharmacokinetic study.

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Simultaneous quantitation of I ...... n for a pharmacokinetic study.

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Simultaneous quantitation of I ...... n for a pharmacokinetic study.

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K Mukkanti

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Kanthikiran V S Varanasi

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Satheeshmanikandan R S Thappali

http://www.w3.org/2001/XMLSchema#string

Sridhar Veeraraghavan

http://www.w3.org/2001/XMLSchema#string

Swaroop Kumar V S Vakkalanka

http://www.w3.org/2001/XMLSchema#string

P2860

Inhibition of phosphoinositide 3-kinase delta attenuates allergic airway inflammation and hyperresponsiveness in murine asthma model

Targeting phosphoinositide-3-kinase-delta with theophylline reverses corticosteroid insensitivity in chronic obstructive pulmonary disease.

Roflumilast attenuates allergen-induced inflammation in mild asthmatic subjects

The p110δ subunit of PI3K regulates bone marrow-derived eosinophil trafficking and airway eosinophilia in allergen-challenged mice.

Novel signal transduction modulators for the treatment of airway diseases.

Roflumilast for COPD.

New therapeutic options in the management of COPD - focus on roflumilast.

Cross talk between phosphatidylinositol 3-kinase and cyclic AMP (cAMP)-protein kinase a signaling pathways at the level of a protein kinase B/beta-arrestin/cAMP phosphodiesterase 4 complex.

The phosphoinositide 3'-kinase p110δ modulates contractile protein production and IL-6 release in human airway smooth muscle.

[Clinical profile of roflumilast].

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1612-1619

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scholarly article

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10.1002/JMS.3103

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23280750

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Simultaneous quantitation of IC87114, roflumilast and its active metabolite roflumilast N-oxide in plasma by LC-MS/MS: application for a pharmacokinetic study.

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P2860

P2860

Simultaneous quantitation of IC87114, roflumilast and its active metabolite roflumilast N-oxide in plasma by LC-MS/MS: application for a pharmacokinetic study.

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